Clinical use of oxygen-enhanced T1 mapping MRI of the lung: Reproducibility and impact of closed versus loose fit oxygen delivery system

Julius Renne, Peer Lauermann, Jan Hinrichs, Christian Schönfeld, Sajoscha Sorrentino, Marcel Gutberlet, Peter Jakob, Frank Wacker, Jens Vogel-Claussen

Research output: Contribution to journalArticle

Abstract

Materials and Methods: Twelve healthy volunteers were examined on two visits with an inversion recovery snapshot fast low angle shot sequence on a 1.5 T system. Coronal slices were obtained breathing room air as well as 100% oxygen with a flow rate of 15 L/min. For oxygen delivery a standard nontight face mask and a full closed air-cushion face mask were used. T1 relaxation times and the oxygen transfer function (OTF) were calculated.

Results: The mean T1 values did not change significantly between the two visits (P>0.05). The T1 values breathing 100% oxygen obtained using the full closed mask were significantly lower (1093±38 msec; P1 values (3.5% vs. 4.5%) as well as the OTF (12.4% vs. 22.0%) and no difference of the OTF on the second visit (P>0.05).

Conclusion: Oxygen-enhanced T1 mapping MRI produces reproducible data when using a full closed face mask.

Purpose: To evaluate the reproducibility of oxygenenhanced magnetic resonance imaging (MRI), and the influence of different gas delivery methods, in a clinical environment.

Original languageEnglish (US)
Pages (from-to)60-66
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Volume41
Issue number1
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Fingerprint

Magnetic Resonance Imaging
Oxygen
Lung
Masks
Respiration
Air
Healthy Volunteers
Gases

Keywords

  • IRsnapshot FLASH
  • Oxygen-enhanced MRI
  • Pulmonary MRI
  • T mapping

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Clinical use of oxygen-enhanced T1 mapping MRI of the lung : Reproducibility and impact of closed versus loose fit oxygen delivery system. / Renne, Julius; Lauermann, Peer; Hinrichs, Jan; Schönfeld, Christian; Sorrentino, Sajoscha; Gutberlet, Marcel; Jakob, Peter; Wacker, Frank; Vogel-Claussen, Jens.

In: Journal of Magnetic Resonance Imaging, Vol. 41, No. 1, 01.01.2015, p. 60-66.

Research output: Contribution to journalArticle

Renne, J, Lauermann, P, Hinrichs, J, Schönfeld, C, Sorrentino, S, Gutberlet, M, Jakob, P, Wacker, F & Vogel-Claussen, J 2015, 'Clinical use of oxygen-enhanced T1 mapping MRI of the lung: Reproducibility and impact of closed versus loose fit oxygen delivery system', Journal of Magnetic Resonance Imaging, vol. 41, no. 1, pp. 60-66. https://doi.org/10.1002/jmri.24535
Renne, Julius ; Lauermann, Peer ; Hinrichs, Jan ; Schönfeld, Christian ; Sorrentino, Sajoscha ; Gutberlet, Marcel ; Jakob, Peter ; Wacker, Frank ; Vogel-Claussen, Jens. / Clinical use of oxygen-enhanced T1 mapping MRI of the lung : Reproducibility and impact of closed versus loose fit oxygen delivery system. In: Journal of Magnetic Resonance Imaging. 2015 ; Vol. 41, No. 1. pp. 60-66.
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