Clinical use of oral contraceptives administered vaginally: A case report

M. Sullivan-Nelson; J. A. Kuller; H. A. Zacur

doi:10.1016/s0015-0282(16)53055-6

Clinical use of oral contraceptives administered vaginally: A case report

M. Sullivan-Nelson, J. A. Kuller, H. A. Zacur

School of Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

This case report describes a patient with acute promyelocytic leukemia receiving high-dose suppressive chemotherapy with well controlled cyclical episodes of vaginal bleeding using combination oral contraceptive pills containing 50 mcg mestranol and 1.0 mg norethindrone (NE). Development of severe hemorrhagic mucocitis during chemotherapy prevented oral drug administration. An amenorrheic state was successfully achieved by daily vaginal administration of twice the oral dose of contraceptive.

Original language	English (US)
Pages (from-to)	864-866
Number of pages	3
Journal	Fertility and sterility
Volume	52
Issue number	5
DOIs	https://doi.org/10.1016/s0015-0282(16)53055-6
State	Published - 1989

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

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title = "Clinical use of oral contraceptives administered vaginally: A case report",

abstract = "This case report describes a patient with acute promyelocytic leukemia receiving high-dose suppressive chemotherapy with well controlled cyclical episodes of vaginal bleeding using combination oral contraceptive pills containing 50 mcg mestranol and 1.0 mg norethindrone (NE). Development of severe hemorrhagic mucocitis during chemotherapy prevented oral drug administration. An amenorrheic state was successfully achieved by daily vaginal administration of twice the oral dose of contraceptive.",

author = "M. Sullivan-Nelson and Kuller, {J. A.} and Zacur, {H. A.}",

note = "Funding Information: Received February 14, 1989; revised and accepted July 19, 1989. * Supported in part by grant HD-06268 from The Population Center and by grant N01-HD-32816 from the National Institutes of Health. t Reprint requests: Howatd A. Zacur, M.D., Ph.D., Park B2-202, The Johns Hopkins Hospital, Baltimore, Maryland 21205.",

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T1 - Clinical use of oral contraceptives administered vaginally

T2 - A case report

AU - Sullivan-Nelson, M.

AU - Kuller, J. A.

AU - Zacur, H. A.

N1 - Funding Information: Received February 14, 1989; revised and accepted July 19, 1989. * Supported in part by grant HD-06268 from The Population Center and by grant N01-HD-32816 from the National Institutes of Health. t Reprint requests: Howatd A. Zacur, M.D., Ph.D., Park B2-202, The Johns Hopkins Hospital, Baltimore, Maryland 21205.

PY - 1989

Y1 - 1989

N2 - This case report describes a patient with acute promyelocytic leukemia receiving high-dose suppressive chemotherapy with well controlled cyclical episodes of vaginal bleeding using combination oral contraceptive pills containing 50 mcg mestranol and 1.0 mg norethindrone (NE). Development of severe hemorrhagic mucocitis during chemotherapy prevented oral drug administration. An amenorrheic state was successfully achieved by daily vaginal administration of twice the oral dose of contraceptive.

AB - This case report describes a patient with acute promyelocytic leukemia receiving high-dose suppressive chemotherapy with well controlled cyclical episodes of vaginal bleeding using combination oral contraceptive pills containing 50 mcg mestranol and 1.0 mg norethindrone (NE). Development of severe hemorrhagic mucocitis during chemotherapy prevented oral drug administration. An amenorrheic state was successfully achieved by daily vaginal administration of twice the oral dose of contraceptive.

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Clinical use of oral contraceptives administered vaginally: A case report

Abstract

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