Clinical trials of riluzole in patients with ALS

R. G. Miller; J. P. Bouchard; P. Duquette; A. Eisen; D. Gelinas; Y. Harati; T. L. Munsat; L. Powe; J. Rothstein; P. Salzman; R. L. Sufit

doi:10.1212/wnl.47.4_suppl_2.86s

Clinical trials of riluzole in patients with ALS

R. G. Miller, J. P. Bouchard, P. Duquette, A. Eisen, D. Gelinas, Y. Harati, T. L. Munsat, L. Powe, J. Rothstein, P. Salzman, R. L. Sufit

School of Medicine

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Abstract

Two double-blinded, placebo-controlled clinical trials of riluzole have now been carried out in more than 1,100 patients with ALS. The results of both studies show a modest benefit in prolonging survival that is statistically significant. These results led to the availability of this drug by the Food and Drug Administration for use in the United States beginning in early 1996. This is the first drug that has been available for ALS. It begins a new era in both basic and clinical research in an attempt to find a cure for this disease.

Original language	English (US)
Pages (from-to)	S86-S92
Journal	Neurology
Volume	47
Issue number	4 SUPPL.
DOIs	https://doi.org/10.1212/wnl.47.4_suppl_2.86s
State	Published - Oct 1996

ASJC Scopus subject areas

Clinical Neurology

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title = "Clinical trials of riluzole in patients with ALS",

abstract = "Two double-blinded, placebo-controlled clinical trials of riluzole have now been carried out in more than 1,100 patients with ALS. The results of both studies show a modest benefit in prolonging survival that is statistically significant. These results led to the availability of this drug by the Food and Drug Administration for use in the United States beginning in early 1996. This is the first drug that has been available for ALS. It begins a new era in both basic and clinical research in an attempt to find a cure for this disease.",

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AU - Miller, R. G.

AU - Bouchard, J. P.

AU - Duquette, P.

AU - Eisen, A.

AU - Gelinas, D.

AU - Harati, Y.

AU - Munsat, T. L.

AU - Powe, L.

AU - Rothstein, J.

AU - Salzman, P.

AU - Sufit, R. L.

PY - 1996/10

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AB - Two double-blinded, placebo-controlled clinical trials of riluzole have now been carried out in more than 1,100 patients with ALS. The results of both studies show a modest benefit in prolonging survival that is statistically significant. These results led to the availability of this drug by the Food and Drug Administration for use in the United States beginning in early 1996. This is the first drug that has been available for ALS. It begins a new era in both basic and clinical research in an attempt to find a cure for this disease.

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Clinical trials of riluzole in patients with ALS

Abstract

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