Clinical Trial of Malaria Prophylaxis in Tropical Splenomegaly Syndrome

Pieter C. Stuiver, John L. Ziegler, John B. Wood, Richard H. Morrow, M. S.R. Hutt

Research output: Contribution to journalArticlepeer-review

Abstract

A controlled, randomized, double-blind trial of malaria prophylaxis in tropical splenomegaly syndrome showed a significant reduction in spleen size and an improvement of anaemia and symptoms in patients treated with antimalarials compared with control subjects receiving placebo. This study confirms the observations from West Africa and provides further indirect evidence for a malarial aetiology of tropical splenomegaly syndrome.

Original languageEnglish (US)
Pages (from-to)426-429
Number of pages4
JournalBritish medical journal
Volume1
Issue number5746
DOIs
StatePublished - Feb 20 1971

ASJC Scopus subject areas

  • Medicine(all)

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