Clinical trends in stent treatment of simple and complex coronary disease

S. Rispler, B. Benari, I. Eizen, E. Grenadier, W. Markiewicz, A. Cohen, R. Beyar

Research output: Contribution to journalArticle

Abstract

This is a retrospective analysis of a consecutive group of patients from a single medical center who underwent stent implantation. It describes 316 patients who constituted 53% of the angioplasty procedures carried out in a single year. The authors describe the complications and their 1-year follow- up. We aimed to study the short and long-term results of stenting in our centre in relation to multiple clinical and angiographic variables. During 1996, 316 consecutive patients were treated with stent implantation for a total of 381 coronary lesions. The pharmacological protocol methods of stent implantation and patient characteristics were used. Clinical variables were: age 59.1 ± 10.7 years, diabetes mellitus 25.3%, hypertension 33.0% and angina pectoris 88.7% (unstable in 44.1%). Previous coronary surgery had been undergone by 9.2%. Multivessel disease was present in 56% of the patients. The indications for stenting were: primary 58.5%, suboptimal results 33.0% and threatened or acute occlusion 8.5%. Angiographic success was 98.9% and clinical success 96.8%. The major inhospital complications were acute myocardial infarction (2.2%), acute revascularization (0.3%) and major bleeding (0.6%). All occurred within 24 h of revascularization. Repeated angiography was performed in 115 cases (30.2%) at 160.3 ± 109.4 days after stent procedure for unstable angina (38.7%), stable angina (26.1%) and other causes (35.2%). The restenosis rate in those catheterized was 38.1%, with an overall clinical restenosis rate of 11.3% during the follow-up period. Restenosis was more prevalent among diabetic patients (17.9 vs 9.15%, P = 0.02) and patients with prior balloon angioplasty (18.6 vs 9.75%, P = 0.046). Clinical follow-up was available in 90.8% of the patients for 291 ± 112 days. The actuarial survival at the end of the follow-up period was 93.8%. Death/myocardial infarction was associated with unstable angina pectoris (P = 0.006), hypertension (P = 0.001), smoking (P = 0.046) and threatened or acute occlusion (P <0.001). In the first year of extensive stent use, stenting is associated with high technical and clinical success rates. Long-term results after stent implantation are associated with the occurrence of acute or threatened occlusion, and the in-hospital complications diabetes mellitus and hypertension.

Original languageEnglish (US)
Pages (from-to)109-115
Number of pages7
JournalInternational Journal of Cardiovascular Interventions
Volume2
Issue number2
StatePublished - 1999
Externally publishedYes

Keywords

  • Coronary artery disease
  • Stents

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Rispler, S., Benari, B., Eizen, I., Grenadier, E., Markiewicz, W., Cohen, A., & Beyar, R. (1999). Clinical trends in stent treatment of simple and complex coronary disease. International Journal of Cardiovascular Interventions, 2(2), 109-115.