Clinical significance of antinuclear antibodies with hypocomplementemia

J. L. Morris, T. M. Zizic, L. E. Shulman, M. B. Stevens

Research output: Contribution to journalArticle

Abstract

Eighty five percent of patients with reduced serum complement and antinuclear antibodies on initial evaluation were found to have systemic lupus erythematosus (SLE). The more marked the degree of complement depression, the more frequent was renal involvement on clinical and histological grounds. In patients with lupus nephritis proven on renal biopsy, with hypocomplementemia, 18% had no clinical or laboratory evidence of renal involvement.

Original languageEnglish (US)
Pages (from-to)321-328
Number of pages8
JournalJohns Hopkins Medical Journal
Volume133
Issue number6
StatePublished - Dec 1 1973

ASJC Scopus subject areas

  • Medicine(all)

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    Morris, J. L., Zizic, T. M., Shulman, L. E., & Stevens, M. B. (1973). Clinical significance of antinuclear antibodies with hypocomplementemia. Johns Hopkins Medical Journal, 133(6), 321-328.