Eighty five percent of patients with reduced serum complement and antinuclear antibodies on initial evaluation were found to have systemic lupus erythematosus (SLE). The more marked the degree of complement depression, the more frequent was renal involvement on clinical and histological grounds. In patients with lupus nephritis proven on renal biopsy, with hypocomplementemia, 18% had no clinical or laboratory evidence of renal involvement.
|Original language||English (US)|
|Number of pages||8|
|Journal||Johns Hopkins Medical Journal|
|State||Published - Dec 1 1973|
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