Clinical results of a pilot study on stereovision-guided stereotactic radiotherapy and intensity modulated radiotherapy

Shidong Li, Lawrence R Kleinberg, Daniele Rigamonti, Moody D. Wharam, Abdul Rashid, Juan Jackson, David Djajaputra, Shenjen He, Tunisia Creasey, Theodore DeWeese

Research output: Contribution to journalArticle

Abstract

Real-time stereovision-guidance has been introduced for efficient and convenient fractionated stereotactic radiotherapy (FSR) and image-guided intensity-modulated radiation therapy (IMRT). This first pilot study is to clinically evaluate its accuracy and precision as well as impact on treatment doses. Sixty-one FSR patients wearing stereotactic masks (SMs) and nine IMRT patients wearing flexible masks (FMs), were accrued. Daily target reposition was initially based-on biplane-radiographs and then adjusted in six degrees of freedom under real-time stereovision guidance. Mean and standard deviation of the head displacements measured the accuracy and precision. Head positions during beam-on times were measured with real-time stereovisions and used for determination of delivered doses. Accuracy ± precision in direction with the largest errors shows improvement from 0.4 ± 2.3 mm to 0.0 ± 1.0 mm in the inferior-to-superior direction for patients wearing SM or from 0.8 ± 4.3 mm to 0.4 ± 1.7 mm in the posterior-to-anterior direction for patients wearing FM. The image-guidance increases target volume coverage by

Original languageEnglish (US)
Pages (from-to)603-617
Number of pages15
JournalTechnology in Cancer Research and Treatment
Volume9
Issue number6
StatePublished - Dec 2010

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Intensity-Modulated Radiotherapy
Masks
Radiotherapy
Head
Image-Guided Radiotherapy
Direction compound
Therapeutics

Keywords

  • Fractionated stereotactic radiotherapy (FSR)
  • Image-guided radiation therapy (IGRT)
  • Intensity modulated radiotherapy (IMRT)
  • Stereovision (3D video imaging)

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Clinical results of a pilot study on stereovision-guided stereotactic radiotherapy and intensity modulated radiotherapy. / Li, Shidong; Kleinberg, Lawrence R; Rigamonti, Daniele; Wharam, Moody D.; Rashid, Abdul; Jackson, Juan; Djajaputra, David; He, Shenjen; Creasey, Tunisia; DeWeese, Theodore.

In: Technology in Cancer Research and Treatment, Vol. 9, No. 6, 12.2010, p. 603-617.

Research output: Contribution to journalArticle

Li, Shidong ; Kleinberg, Lawrence R ; Rigamonti, Daniele ; Wharam, Moody D. ; Rashid, Abdul ; Jackson, Juan ; Djajaputra, David ; He, Shenjen ; Creasey, Tunisia ; DeWeese, Theodore. / Clinical results of a pilot study on stereovision-guided stereotactic radiotherapy and intensity modulated radiotherapy. In: Technology in Cancer Research and Treatment. 2010 ; Vol. 9, No. 6. pp. 603-617.
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