Clinical research in systemic lupus erythematosus: Immediate relevance to clinical practice

Research output: Contribution to journalArticle


Systemic lupus erythematosus remains a challenge because of its diverse presentations, variable natural history, and lack of uniform response to treatment. True remission is very rare. Reliance on corticosteroid treatment leads to unwanted long-term toxicity. Great advances have been made in the early detection of lupus nephritis and in treatment. Greater appreciation of cognitive impairment and of lupus myelitis is now possible. Pregnancy risks are better characterized. However, the greatest unmet challenge remains atherosclerosis.

Original languageEnglish (US)
Pages (from-to)1-5
Number of pages5
JournalInternational Journal of Rheumatic Diseases
Issue number1
Publication statusPublished - Feb 2011



  • Lupus nephritis
  • Lupus pregnancy
  • SLE

ASJC Scopus subject areas

  • Rheumatology

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