Clinical predictors of postoperative hemoglobin drift

Michael C. Grant, Glenn Whitman, Will J. Savage, Paul Michael Ness, Steven Mark Frank

Research output: Contribution to journalArticle

Abstract

Background The decision to transfuse red blood cells in surgical patients should be based on multiple clinical variables, rather than on isolated hemoglobin (Hb) measurements alone. An important but often unrecognized clinical variable is the postoperative downward drift in Hb concentration (Hb drift), but the etiology, predictors, and time course of Hb drift are not well understood. Study Design and Methods Data were retrospectively collected for patients who did not receive postoperative transfusion. Initially, 11 common surgical procedures from one institution (n=3179) were compared to assess clinical predictors of Hb drift. Data were analyzed in detail for two procedures associated with a large Hb drift (Whipple [n=82] and lumbar spinal fusion [n=74]), to determine the clinical predictors and temporal pattern of postoperative Hb drift. Results Surgical procedures with greater intraoperative intravenous (IV) fluid and blood requirements had greater postoperative Hb drift. The maximum Hb drifts after the Whipple and spinal fusion procedures were -2.5±1.1g/dL (occurring on Day4, p

Original languageEnglish (US)
Pages (from-to)1460-1468
Number of pages9
JournalTransfusion
Volume54
Issue number6
DOIs
StatePublished - 2014

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Hemoglobins
Spinal Fusion
Erythrocytes

ASJC Scopus subject areas

  • Hematology
  • Immunology
  • Immunology and Allergy

Cite this

Clinical predictors of postoperative hemoglobin drift. / Grant, Michael C.; Whitman, Glenn; Savage, Will J.; Ness, Paul Michael; Frank, Steven Mark.

In: Transfusion, Vol. 54, No. 6, 2014, p. 1460-1468.

Research output: Contribution to journalArticle

Grant, Michael C. ; Whitman, Glenn ; Savage, Will J. ; Ness, Paul Michael ; Frank, Steven Mark. / Clinical predictors of postoperative hemoglobin drift. In: Transfusion. 2014 ; Vol. 54, No. 6. pp. 1460-1468.
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