TY - JOUR
T1 - Clinical Pharmacokinetics in the Treatment of Rheumatoid Arthritis in Pregnancy
AU - Witter, Frank R.
PY - 1993/12
Y1 - 1993/12
N2 - Rheumatoid arthritis is a relatively common problem in women of reproductive age. Pregnancy may affect all aspects of the pharmacokinetics of the drugs used in its treatment. The effects of pregnancy on the pharmacokinetics of drugs are, for the most part, not clinically significant. The pharmacokinetics of placental transfer and fetal safety have been specified for many drugs. Drugs used in rheumatoid arthritis can be classified into 3 classes: those with the greatest safety for the fetus, those that are unsafe for the fetus, and those for which there are insufficient data to determine the risk to the fetus.
AB - Rheumatoid arthritis is a relatively common problem in women of reproductive age. Pregnancy may affect all aspects of the pharmacokinetics of the drugs used in its treatment. The effects of pregnancy on the pharmacokinetics of drugs are, for the most part, not clinically significant. The pharmacokinetics of placental transfer and fetal safety have been specified for many drugs. Drugs used in rheumatoid arthritis can be classified into 3 classes: those with the greatest safety for the fetus, those that are unsafe for the fetus, and those for which there are insufficient data to determine the risk to the fetus.
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U2 - 10.2165/00003088-199325060-00004
DO - 10.2165/00003088-199325060-00004
M3 - Review article
C2 - 8119046
AN - SCOPUS:0027486201
SN - 0312-5963
VL - 25
SP - 444
EP - 449
JO - Clinical Pharmacokinetics
JF - Clinical Pharmacokinetics
IS - 6
ER -