Clinical pattern of toxoplasmic retinochoroiditis in a Spanish referral center

Amanda Rey, Victor Llorenç, Laura Pelegrín, Marina Mesquida, Blanca Molins, José Rios, J Fernando Arevalo, Alfredo Adán

Research output: Contribution to journalArticle

Abstract

Background/Aims: To analyze the clinical pattern of ocular toxoplasmosis in a referral center in Spain. Methods: The medical records of consecutive patients with ocular toxoplasmosis admitted from a single referral center for uveitis in Barcelona (Spain) were retrospectively analyzed between January 2005 and January 2011. Results: One hundred and thirteen eyes from 113 patients (74 Spanish and 39 South American) with active ocular toxoplasmosis were analyzed with a 12-month follow-up. Final BCVA ≤20/200 was found in 30 eyes (26.5%). The most frequent complications were macular edema (16.8%) and epiretinal membrane (11.5%). Anterior chamber cell scores of ≥2+ (p = 0.003), vitreous cell scores of ≥2+ (p = 0.001), and the presence of cataracts (p = 0.047) or serous retinal detachment (p = 0.008) were more common among the South American than Spanish cohort. Active macular lesions (p <0.001) with an initial BCVA ≤20/200 (p <0.001) and advanced age (p = 0.019) were predictors for final BCVA ≤20/200, whereas female gender (p = 0.021) and an initial BCVA ≤20/200 (p = 0.045) were predictors for ocular complications. Moreover, a BCVA ≤20/200 (p <0.001) and a vitreous cell score of ≥2+ (p = 0.045) at the initial examination were predictors of an eventual need for ocular surgery. Conclusion: The clinical features of ocular toxoplasmosis in Spanish patients differ from those of South American patients. In general, active macular lesions with an initial BCVA ≤20/200 and advanced age were shown to be predictors for final BCVA ≤20/200 in our patient cohort.

Original languageEnglish (US)
Pages (from-to)173-178
Number of pages6
JournalOphthalmologica
Volume229
Issue number3
DOIs
StatePublished - Apr 2013

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Ocular Toxoplasmosis
Referral and Consultation
Spain
Epiretinal Membrane
Macular Edema
Uveitis
Anterior Chamber
Retinal Detachment
Hispanic Americans
Cataract
Medical Records

Keywords

  • Ocular toxoplasmosis
  • Retinochoroiditis
  • Toxoplasma gondii
  • Uveitis

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Rey, A., Llorenç, V., Pelegrín, L., Mesquida, M., Molins, B., Rios, J., ... Adán, A. (2013). Clinical pattern of toxoplasmic retinochoroiditis in a Spanish referral center. Ophthalmologica, 229(3), 173-178. https://doi.org/10.1159/000348740

Clinical pattern of toxoplasmic retinochoroiditis in a Spanish referral center. / Rey, Amanda; Llorenç, Victor; Pelegrín, Laura; Mesquida, Marina; Molins, Blanca; Rios, José; Arevalo, J Fernando; Adán, Alfredo.

In: Ophthalmologica, Vol. 229, No. 3, 04.2013, p. 173-178.

Research output: Contribution to journalArticle

Rey, A, Llorenç, V, Pelegrín, L, Mesquida, M, Molins, B, Rios, J, Arevalo, JF & Adán, A 2013, 'Clinical pattern of toxoplasmic retinochoroiditis in a Spanish referral center', Ophthalmologica, vol. 229, no. 3, pp. 173-178. https://doi.org/10.1159/000348740
Rey A, Llorenç V, Pelegrín L, Mesquida M, Molins B, Rios J et al. Clinical pattern of toxoplasmic retinochoroiditis in a Spanish referral center. Ophthalmologica. 2013 Apr;229(3):173-178. https://doi.org/10.1159/000348740
Rey, Amanda ; Llorenç, Victor ; Pelegrín, Laura ; Mesquida, Marina ; Molins, Blanca ; Rios, José ; Arevalo, J Fernando ; Adán, Alfredo. / Clinical pattern of toxoplasmic retinochoroiditis in a Spanish referral center. In: Ophthalmologica. 2013 ; Vol. 229, No. 3. pp. 173-178.
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