Abstract
Purpose: To describe the clinical characteristics and treatment outcomes of Vogt–Koyanagi–Harada (VKH) disease over a 12-year period. Methods: A retrospective chart review was used to identify VKH patients, from January 1999 to December 2011. Results: In total, 154 patients (308 eyes) were diagnosed with VKH. The mean age at diagnosis was 33.8 ± 13 years. Mean baseline best-corrected visual acuity (BCVA) was 20/125; (0.8 ± 0.6 logMAR). Recurrent episodes occurred in 107 (54%) patients. Oral prednisone was administered in all patients. At the last visit, the mean BCVA was 20/50 (0.4 ± 0.7 logMAR). The most common complications post-treatment were: glaucoma [104 (33.8%) eyes] and cataract [84 (27.2%) eyes]. Conclusions: In Saudi Arabia, VKH-related uveitis is predominant in young females. Bilateral panuveitis is the most common ocular manifestation and near 50% of eyes present with exudative retinal detachment. Oral prednisone was the primary treatment and the majority of eyes maintained 20/50 or better vision.
Original language | English (US) |
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Pages (from-to) | 521-529 |
Number of pages | 9 |
Journal | Ocular Immunology and Inflammation |
Volume | 24 |
Issue number | 5 |
DOIs | |
State | Published - Sep 2 2016 |
Keywords
- Panuveitis
- Saudi Arabia
- Vogt–Koyanagi–Harada disease
- prednisone
- uveitis
ASJC Scopus subject areas
- Immunology and Allergy
- Ophthalmology