Clinical neurological assessment of the critically ill patient

Raoul Sutter, Tarek Sharshar, Robert David Stevens

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Neurological assessment of critically ill patients requires physical examination, although sensitivity and specificity of findings may be limited by co-existing cognitive impairment, sedative or paralytic medication, endotracheal intubation, mechanical ventilation, neuromuscular weakness, and injuries or surgery involving extracranial tissues. Neurological signs and syndromes are fundamental indicators of severity of illness and prognosis. Neurological syndromes commonly seen in intensive care unit (ICU) patients include disturbances in consciousness, delirium, seizures, generalized weakness, and focal neurological deficits. Neurological examination in responsive patients should include an assessment of mental status, attention, cranial nerves, motor, and sensory findings. If there is persisting diagnostic uncertainty, additional testing should be performed. Computed tomography of the head should be performed if there is a new onset of seizures, focal neurological deficits, and if there is an unexplained alteration of mental status or loss of consciousness. Brain magnetic resonance imaging has greater sensitivity for hyperacute ischemic stroke, microhemorrhagic lesions, anoxic-ischemic damage, and alterations of the white matter and the brainstem. Electroencephalography is needed if seizures or status epilepticus are suspected as a cause or consequence of acute brain dysfunction. Electromyography, nerve conduction velocities, and, in selected patients, cerebrospinal fluid (CSF) examination should be obtained when neuromuscular weakness is severe or cannot be assessed clinically. Physical examination is the cornerstone in the neurological assessment of critically ill patients, however, the validity and reliability of this examination is constrained by concurrent cognitive impairment and the effects of sedative or paralytic medication. Endotracheal intubation and mechanical ventilation pose significant obstacles to the assessment of cognitive (and in particular language) disturbances and to the interpretation of pathological breathing patterns. Neuromuscular weakness acquired in the ICU, and injuries or surgery may significantly limit the response to stimulation and the yield of neurological assessment [1]. Notwithstanding these constraints, neurological signs remain valuable indicators of severity of illness and prognosis [2–4].

Original languageEnglish (US)
Title of host publicationBrain Disorders in Critical Illness: Mechanisms, Diagnosis, and Treatment
PublisherCambridge University Press
Pages219-228
Number of pages10
ISBN (Print)9781139248822, 9781107029194
DOIs
StatePublished - Jan 1 2011

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Critical Illness
Seizures
Intratracheal Intubation
Hypnotics and Sedatives
Artificial Respiration
Physical Examination
Intensive Care Units
Unconsciousness
Delirium
Cranial Nerves
Status Epilepticus
Neural Conduction
Wounds and Injuries
Neurologic Examination
Brain
Electromyography
Consciousness
Reproducibility of Results
Brain Stem
Uncertainty

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sutter, R., Sharshar, T., & Stevens, R. D. (2011). Clinical neurological assessment of the critically ill patient. In Brain Disorders in Critical Illness: Mechanisms, Diagnosis, and Treatment (pp. 219-228). Cambridge University Press. https://doi.org/10.1017/CBO9781139248822.026

Clinical neurological assessment of the critically ill patient. / Sutter, Raoul; Sharshar, Tarek; Stevens, Robert David.

Brain Disorders in Critical Illness: Mechanisms, Diagnosis, and Treatment. Cambridge University Press, 2011. p. 219-228.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sutter, R, Sharshar, T & Stevens, RD 2011, Clinical neurological assessment of the critically ill patient. in Brain Disorders in Critical Illness: Mechanisms, Diagnosis, and Treatment. Cambridge University Press, pp. 219-228. https://doi.org/10.1017/CBO9781139248822.026
Sutter R, Sharshar T, Stevens RD. Clinical neurological assessment of the critically ill patient. In Brain Disorders in Critical Illness: Mechanisms, Diagnosis, and Treatment. Cambridge University Press. 2011. p. 219-228 https://doi.org/10.1017/CBO9781139248822.026
Sutter, Raoul ; Sharshar, Tarek ; Stevens, Robert David. / Clinical neurological assessment of the critically ill patient. Brain Disorders in Critical Illness: Mechanisms, Diagnosis, and Treatment. Cambridge University Press, 2011. pp. 219-228
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