Abstract
The objective of this article is to review our current understanding of the role of IgE (reaginic) antibodies in immediate hypersensitivity (allergic) reactions in humans and to summarize recent approaches in the laboratory diagnosis and management of human allergic diseases. Quantitative assays for total and allergen-specific IgE antibodies will be discussed within the context of their use in diagnosis. The RAST (radioallergosorbent test) inhibition assay and specific IgG antibody assays will then be described as methods useful in the planning and monitoring of hyposensitization regimens (immunotherapy).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 117-138 |
| Number of pages | 22 |
| Journal | Clinics in laboratory medicine |
| Volume | 6 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1986 |
| Externally published | Yes |
ASJC Scopus subject areas
- Clinical Biochemistry
- Biochemistry, medical