Abstract
The objective of this article is to review our current understanding of the role of IgE (reaginic) antibodies in immediate hypersensitivity (allergic) reactions in humans and to summarize recent approaches in the laboratory diagnosis and management of human allergic diseases. Quantitative assays for total and allergen-specific IgE antibodies will be discussed within the context of their use in diagnosis. The RAST (radioallergosorbent test) inhibition assay and specific IgG antibody assays will then be described as methods useful in the planning and monitoring of hyposensitization regimens (immunotherapy).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 117-138 |
| Number of pages | 22 |
| Journal | Clinics in Laboratory Medicine |
| Volume | 6 |
| Issue number | 1 |
| State | Published - 1986 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Medicine(all)
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Clinical laboratory methods for the assessment and management of human allergic diseases. / Hamilton, Robert G; Adkinson, N Franklin.
In: Clinics in Laboratory Medicine, Vol. 6, No. 1, 1986, p. 117-138.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical laboratory methods for the assessment and management of human allergic diseases
AU - Hamilton, Robert G
AU - Adkinson, N Franklin
PY - 1986
Y1 - 1986
N2 - The objective of this article is to review our current understanding of the role of IgE (reaginic) antibodies in immediate hypersensitivity (allergic) reactions in humans and to summarize recent approaches in the laboratory diagnosis and management of human allergic diseases. Quantitative assays for total and allergen-specific IgE antibodies will be discussed within the context of their use in diagnosis. The RAST (radioallergosorbent test) inhibition assay and specific IgG antibody assays will then be described as methods useful in the planning and monitoring of hyposensitization regimens (immunotherapy).
AB - The objective of this article is to review our current understanding of the role of IgE (reaginic) antibodies in immediate hypersensitivity (allergic) reactions in humans and to summarize recent approaches in the laboratory diagnosis and management of human allergic diseases. Quantitative assays for total and allergen-specific IgE antibodies will be discussed within the context of their use in diagnosis. The RAST (radioallergosorbent test) inhibition assay and specific IgG antibody assays will then be described as methods useful in the planning and monitoring of hyposensitization regimens (immunotherapy).
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UR - http://www.scopus.com/inward/citedby.url?scp=0022897283&partnerID=8YFLogxK
M3 - Article
C2 - 3514095
AN - SCOPUS:0022897283
VL - 6
SP - 117
EP - 138
JO - Clinics in Laboratory Medicine
JF - Clinics in Laboratory Medicine
SN - 0272-2712
IS - 1
ER -