Clinical laboratory methods for the assessment and management of human allergic diseases

R. G. Hamilton; N. F. Adkinson

doi:10.1016/s0272-2712(18)30829-1

Clinical laboratory methods for the assessment and management of human allergic diseases

Research output: Contribution to journal › Review article › peer-review

Abstract

The objective of this article is to review our current understanding of the role of IgE (reaginic) antibodies in immediate hypersensitivity (allergic) reactions in humans and to summarize recent approaches in the laboratory diagnosis and management of human allergic diseases. Quantitative assays for total and allergen-specific IgE antibodies will be discussed within the context of their use in diagnosis. The RAST (radioallergosorbent test) inhibition assay and specific IgG antibody assays will then be described as methods useful in the planning and monitoring of hyposensitization regimens (immunotherapy).

Original language	English (US)
Pages (from-to)	117-138
Number of pages	22
Journal	Clinics in laboratory medicine
Volume	6
Issue number	1
DOIs	https://doi.org/10.1016/s0272-2712(18)30829-1
State	Published - 1986
Externally published	Yes

ASJC Scopus subject areas

Clinical Biochemistry
Biochemistry, medical

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abstract = "The objective of this article is to review our current understanding of the role of IgE (reaginic) antibodies in immediate hypersensitivity (allergic) reactions in humans and to summarize recent approaches in the laboratory diagnosis and management of human allergic diseases. Quantitative assays for total and allergen-specific IgE antibodies will be discussed within the context of their use in diagnosis. The RAST (radioallergosorbent test) inhibition assay and specific IgG antibody assays will then be described as methods useful in the planning and monitoring of hyposensitization regimens (immunotherapy).",

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year = "1986",

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AU - Adkinson, N. F.

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AB - The objective of this article is to review our current understanding of the role of IgE (reaginic) antibodies in immediate hypersensitivity (allergic) reactions in humans and to summarize recent approaches in the laboratory diagnosis and management of human allergic diseases. Quantitative assays for total and allergen-specific IgE antibodies will be discussed within the context of their use in diagnosis. The RAST (radioallergosorbent test) inhibition assay and specific IgG antibody assays will then be described as methods useful in the planning and monitoring of hyposensitization regimens (immunotherapy).

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