Clinical importance of precursor lesions in the pancreas

Ralph H. Hruban; Kyoichi Takaori; Marcia Canto; Elliot K. Fishman; Kurtis Campbell; Kieran Brune; Scott E. Kern; Michael Goggins

doi:10.1007/s00534-006-1170-9

Clinical importance of precursor lesions in the pancreas

Ralph H. Hruban, Kyoichi Takaori, Marcia Canto, Elliot K. Fishman, Kurtis Campbell, Kieran Brune, Scott E. Kern, Michael Goggins

School of Medicine

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

Three distinct noninvasive precursor lesions to invasive ductal adenocarcinoma of the pancreas have been described. These include the mucinous cystic neoplasm, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia. The early detection and treatment of these lesions can interrupt the progression of a curable noninvasive precursor to an almost uniformly deadly invasive cancer.

Original language	English (US)
Pages (from-to)	255-263
Number of pages	9
Journal	Journal of Hepato-Biliary-Pancreatic Surgery
Volume	14
Issue number	3
DOIs	https://doi.org/10.1007/s00534-006-1170-9
State	Published - May 2007

Keywords

Cancer
Intraductal papillary mucinous neoplasm
Mucinous cystic neoplasm
Pancreas
Pancreatic intraepithelial neoplasia
Precursor

ASJC Scopus subject areas

Surgery
Hepatology

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10.1007/s00534-006-1170-9

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title = "Clinical importance of precursor lesions in the pancreas",

abstract = "Three distinct noninvasive precursor lesions to invasive ductal adenocarcinoma of the pancreas have been described. These include the mucinous cystic neoplasm, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia. The early detection and treatment of these lesions can interrupt the progression of a curable noninvasive precursor to an almost uniformly deadly invasive cancer.",

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AU - Hruban, Ralph H.

AU - Takaori, Kyoichi

AU - Canto, Marcia

AU - Fishman, Elliot K.

AU - Campbell, Kurtis

AU - Brune, Kieran

AU - Kern, Scott E.

AU - Goggins, Michael

PY - 2007/5

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AB - Three distinct noninvasive precursor lesions to invasive ductal adenocarcinoma of the pancreas have been described. These include the mucinous cystic neoplasm, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia. The early detection and treatment of these lesions can interrupt the progression of a curable noninvasive precursor to an almost uniformly deadly invasive cancer.

KW - Cancer

KW - Intraductal papillary mucinous neoplasm

KW - Mucinous cystic neoplasm

KW - Pancreas

KW - Pancreatic intraepithelial neoplasia

KW - Precursor

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Clinical importance of precursor lesions in the pancreas

Abstract

Keywords

ASJC Scopus subject areas

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