Clinical importance of precursor lesions in the pancreas

Ralph H. Hruban, Kyoichi Takaori, Marcia Canto, Elliot K. Fishman, Kurtis Campbell, Kieran Brune, Scott E. Kern, Michael Goggins

Research output: Contribution to journalArticlepeer-review

61 Scopus citations


Three distinct noninvasive precursor lesions to invasive ductal adenocarcinoma of the pancreas have been described. These include the mucinous cystic neoplasm, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia. The early detection and treatment of these lesions can interrupt the progression of a curable noninvasive precursor to an almost uniformly deadly invasive cancer.

Original languageEnglish (US)
Pages (from-to)255-263
Number of pages9
JournalJournal of Hepato-Biliary-Pancreatic Surgery
Issue number3
StatePublished - May 2007


  • Cancer
  • Intraductal papillary mucinous neoplasm
  • Mucinous cystic neoplasm
  • Pancreas
  • Pancreatic intraepithelial neoplasia
  • Precursor

ASJC Scopus subject areas

  • Surgery
  • Hepatology


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