Clinical experience with a collagen-impregnated knitted Dacron vascular graft

J. A. Freischlag, W. S. Moore

Research output: Contribution to journalArticle

Abstract

This report describes our first clinical experience with collagen-impregnated Dacron grafts in the aortic position. Fifty-four consecutive patients (43 men and 11 women), average age 67.5 years (44-84), received 11 tube grafts and 23 bifurcated grafts for abdominal aortic aneurysm replacement, 17 bifurcated grafts for aortic occlusive disease, two grafts for aortic pseudoaneurysm, and one graft for thoracoabdominal aneurysm repair. No preclotting maneuvers were used and there was no blood leak from the fabric upon restoration of blood flow, in spite of the use of systemic heparin. The hospital transfusion rate averaged 1.2 units in patients with occlusive disease and 2.7 units in patients undergoing aneurysm resection, which were similar to the transfusion rate in patients receiving standard knitted grafts prior to this study. There were two postoperative deaths from a myocardial infarction and a cerebral hemorrhage and no perioperative thromboembolic events. During a follow-up averaging 41.5 months (26-59), there were two late graft limb thromboses secondary to outflow disease progression. One patient died of aspiration two months postoperatively. Four patients died secondary to cardiac disease in at 13 and 21 months with functioning grafts. The rest of the patients are alive with functioning grafts. We conclude that the collagen-impregnated Dacron graft obviates the need for preclotting maneuvers because of a zero functional porosity.

Original languageEnglish (US)
Pages (from-to)449-454
Number of pages6
JournalAnnals of Vascular Surgery
Volume4
Issue number5
StatePublished - 1990
Externally publishedYes

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Polyethylene Terephthalates
Blood Vessels
Collagen
Transplants
Aneurysm
Aortic Diseases
Porosity
False Aneurysm
Abdominal Aortic Aneurysm
Cerebral Hemorrhage
Disease Progression
Heparin
Heart Diseases
Thrombosis
Extremities
Myocardial Infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Clinical experience with a collagen-impregnated knitted Dacron vascular graft. / Freischlag, J. A.; Moore, W. S.

In: Annals of Vascular Surgery, Vol. 4, No. 5, 1990, p. 449-454.

Research output: Contribution to journalArticle

Freischlag, J. A. ; Moore, W. S. / Clinical experience with a collagen-impregnated knitted Dacron vascular graft. In: Annals of Vascular Surgery. 1990 ; Vol. 4, No. 5. pp. 449-454.
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