Abstract
Methods to obtain pressure-volume loops in humans and their application to clinical diagnosis and treatment of cardiac disease are discussed. The method employs a conductance catheter, micromanometer, and inferior vena caval balloon occluder to reversibly and rapidly vary venous return. Multiple cardiac cycles measured during this manoeuvre are used to derive a variety of systolic and diastolic function indices, as well as estimates of vascular loading, and cardiac energetics. Strengths and weaknesses of the method as well as pressure-volume indexes themselves are briefly discussed. Lastly, three clinical examples are presented which serve to demonstrate how pressure-volume analysis can provide useful clinical information regarding diagnosis and/or treatment in subjects with heart failure symptoms.
Original language | English (US) |
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Pages (from-to) | 57-64 |
Number of pages | 8 |
Journal | European heart journal |
Volume | 13 |
Issue number | SUPPL. E |
DOIs | |
State | Published - Jan 1 1992 |
Keywords
- Congestive heart failure
- Diastole
- Human heart failure
- Impedance volumetry
- Pressure-volume relations
- Ventricular function
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine