Clinical evaluation of immunological methods for detection of serum prostatic acid phosphatase

J. E. Pontes, B. K. Choe, N. R. Rose, C. Ercole, J. M. Pierce

Research output: Contribution to journalArticlepeer-review

Abstract

Evaluation of serum acid phosphatase by 3 immunochemical methods (radioimmunoassay, counterimmunoelectrophoresis and immunoenzymoassay was done in 3 groups of patients. In 42 patients with stage D prostatic carcinoma a comparison of serum acid phosphatase determination by colorimetric assay and the 3 immunochemical methods in samples obtained before and after initiation of therapy showed an excellent correlation among the assays. Presently, we see no advantage of the immunochemical methods over the colorimetric assay in this group of patients. Among 100 patients studied in a blind fashion to detect those with unsuspected prostatic carcinoma no such cases were found. In the last group of patients with localized prostatic carcinoma staged surgically by pelvic lymphadenectomy the only elevations of serum acid phosphatase were observed in patients with extraprostatic involvement.

Original languageEnglish (US)
Pages (from-to)363-365
Number of pages3
JournalUnknown Journal
Volume126
Issue number3
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Urology

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