Clinical evaluation of 2 point-of-care lateral flow tests for the diagnosis of syphilis

Edith Nakku-Joloba, Agnes Kiragga, Joshua Kimeze Mbazira, Fred Kambugu, Mary Jett-Goheen, Rosalind Parkes Ratanshi, Charlotte Gaydos, Yukari C. Manabe

Research output: Contribution to journalArticlepeer-review

Abstract

A diagnostic performance study comparing the only Food and Drug Administration-approved, point-of-care (POC) treponemal test (Syphilis Health Check) and the World Health Organization pre-qualified SD Bioline POC treponemal test against a treponemal hemagglutination test (TPHA) and a sequential algorithm of nontreponemal rapid plasma reagin and TPHA found both POC tests had <85% sensitivity compared with the TPHA and <85% sensitivity and <95% specificity compared with the rapid plasma reagin and TPHA standards.

Original languageEnglish (US)
Pages (from-to)623-625
Number of pages3
JournalSexually transmitted diseases
Volume43
Issue number10
DOIs
StatePublished - Sep 15 2016

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases

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