Since 1990, over 6000 patients in 23 countries have undergone transmyocardial laser revascularization for the treatment of myocardial ischemia due to end-stage coronary artery disease. To evaluate the efficacy of this procedure, four prospective, randomized, controlled clinical trials have compared transmyocardial laser revascularization to maximal medical therapy. All of the trials demonstrated that transmyocardial laser revascularization provided significant relief of angina when compared to medical management. Additional objective data in the form of exercise tolerance and myocardial perfusion scanning is used to support the symptomatic improvement. The entry criteria for these trials were similar, but the methodology was not. This review provides an update and comparison of the results.
|Original language||English (US)|
|Journal||Cardiovascular Reviews and Reports|
|State||Published - Dec 1 2000|
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine