Clinical course of recurrent respiratory papillomatosis in Danish children

Michael J. Silverberg, Poul Thorsen, Henning Lindeberg, Linda Ahdieh-Grant, Keerti V. Shah

Research output: Contribution to journalArticle

Abstract

Objective: To evaluate the clinical course of juvenile-onset recurrent respiratory papillomatosis (RP) with respect to age, disease duration, and maternal condylomas. Design: Inception cohort study. Setting: All ear, nose, and throat departments in public Danish hospitals. Patients: Fifty-seven Danish children diagnosed with RP and born between 1974 and 1993 were observed for an average of 14 years after diagnosis. Main Outcome Measure: Removal of respiratory papillomas by knife biopsy, laser surgery, or cryotherapy. Results: Children younger than 5 years diagnosed with RP underwent an average of 4.1 surgeries in the first year of disease, the highest rate among all our patients. The overall surgery rate decreased over time after initial diagnosis but remained significantly higher for children with a younger age of onset for the first 4 years of disease (P

Original languageEnglish (US)
Pages (from-to)711-716
Number of pages6
JournalArchives of Otolaryngology--Head and Neck Surgery
Volume130
Issue number6
DOIs
StatePublished - Jun 2004

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Cryotherapy
Public Hospitals
Papilloma
Laser Therapy
Pharynx
Age of Onset
Nose
Ear
Cohort Studies
Mothers
Outcome Assessment (Health Care)
Biopsy
Recurrent respiratory papillomatosis

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Clinical course of recurrent respiratory papillomatosis in Danish children. / Silverberg, Michael J.; Thorsen, Poul; Lindeberg, Henning; Ahdieh-Grant, Linda; Shah, Keerti V.

In: Archives of Otolaryngology--Head and Neck Surgery, Vol. 130, No. 6, 06.2004, p. 711-716.

Research output: Contribution to journalArticle

Silverberg, MJ, Thorsen, P, Lindeberg, H, Ahdieh-Grant, L & Shah, KV 2004, 'Clinical course of recurrent respiratory papillomatosis in Danish children', Archives of Otolaryngology--Head and Neck Surgery, vol. 130, no. 6, pp. 711-716. https://doi.org/10.1001/archotol.130.6.711
Silverberg, Michael J. ; Thorsen, Poul ; Lindeberg, Henning ; Ahdieh-Grant, Linda ; Shah, Keerti V. / Clinical course of recurrent respiratory papillomatosis in Danish children. In: Archives of Otolaryngology--Head and Neck Surgery. 2004 ; Vol. 130, No. 6. pp. 711-716.
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