Clinical correlates of lateral ventricular enlargement in bipolar affective disorder

Godfrey Pearlson; D. J. Garbacz; R. H. Tompkins; Hyo S Ahn; D. F. Gutterman; A. E. Veroff; J. R. DePaulo

doi:10.1176/ajp.141.2.253

Clinical correlates of lateral ventricular enlargement in bipolar affective disorder

Godfrey Pearlson, D. J. Garbacz, R. H. Tompkins, Hyo S Ahn, D. F. Gutterman, A. E. Veroff, J. R. DePaulo

School of Medicine

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63 Scopus citations

Abstract

The presence of lateral ventricular enlargement in some manic-depressive subjects, as assessed by ventricular-brain ratios (VBRs), has been reported. A study of 27 bipolar patients and 27 individually matched normal controls confirmed that finding. Bipolar patients had significantly larger VBRs than did controls. Clinical measures associated with the presence of ventricular enlargement in the bipolar patients included more frequent hospitalizations and histories of persistent unemployment. Other measures of illness severity or social deterioration were not significantly associated with large VBR.

Original language	English (US)
Pages (from-to)	253-256
Number of pages	4
Journal	American Journal of Psychiatry
Volume	141
Issue number	2
DOIs	https://doi.org/10.1176/ajp.141.2.253
State	Published - 1984

ASJC Scopus subject areas

Psychiatry and Mental health

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10.1176/ajp.141.2.253

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title = "Clinical correlates of lateral ventricular enlargement in bipolar affective disorder",

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author = "Godfrey Pearlson and Garbacz, {D. J.} and Tompkins, {R. H.} and Ahn, {Hyo S} and Gutterman, {D. F.} and Veroff, {A. E.} and DePaulo, {J. R.}",

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AU - Garbacz, D. J.

AU - Tompkins, R. H.

AU - Ahn, Hyo S

AU - Gutterman, D. F.

AU - Veroff, A. E.

AU - DePaulo, J. R.

PY - 1984

Y1 - 1984

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Clinical correlates of lateral ventricular enlargement in bipolar affective disorder

Abstract

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