TY - JOUR
T1 - Clinical color vision testing and correlation with visual function
AU - Zhao, Jiawei
AU - Davé, Sarita B.
AU - Wang, Jiangxia
AU - Subramanian, Prem S.
N1 - Funding Information:
All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Financial Disclosures: J.W.: NEI, grant support; P.S.S.: NEI, grant support; US Department of Defense, grant support; Stryker Corp (Kalamazoo, Michigan), grant support; Novartis AG (Basel, Switzerland), grant support; National Aeronautics and Space Administration, consultant; Wolters Kluwer (Baltimore, Maryland), royalties; CME Solutions, Inc (Tucson, Arizona), payment for educational material development, travel expenses for meeting presentations; various law firms, expert witness testimony. Funding/Support: Supported in part by an unrestricted grant to the Wilmer Eye Institute from Research to Prevent Blindness, USA and Wilmer Biostatistics Core Grant EY01765. All authors attest that they meet the current ICMJE requirements to qualify as authors.
Publisher Copyright:
© 2015 Elsevier Inc. All rights reserved.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Purpose To determine if Hardy-Rand-Rittler (H-R-R) and Ishihara testing are accurate estimates of color vision in subjects with acquired visual dysfunction. Design Assessment of diagnostic tools. Methods Twenty-two subjects with optic neuropathy (aged 18-65) and 18 control subjects were recruited prospectively from an outpatient clinic. Individuals with visual acuity (VA) <20/200 or with congenital color blindness were excluded. All subjects underwent a comprehensive eye examination including VA, color vision, and contrast sensitivity testing. Color vision was assessed using H-R-R and Ishihara plates and Farnsworth D-15 (D-15) discs. D-15 is the accepted standard for detecting and classifying color vision deficits. Contrast sensitivity was measured using Pelli-Robson contrast sensitivity charts. Results No relationship was found between H-R-R and D-15 scores (P =.477). H-R-R score and contrast sensitivity were positively correlated (P =.003). On multivariate analysis, contrast sensitivity (β = 8.61, P <.001) and VA (β = 2.01, P =.022) both showed association with H-R-R scores. Similar to H-R-R, Ishihara score did not correlate with D-15 score (P =.973), but on multivariate analysis was related to contrast sensitivity (β = 8.69, P <.001). H-R-R and Ishihara scores had an equivalent relationship with contrast sensitivity (P =.069). Conclusion Neither H-R-R nor Ishihara testing appears to assess color identification in patients with optic neuropathy. Both H-R-R and Ishihara testing are correlated with contrast sensitivity, and these tests may be useful clinical surrogates for contrast sensitivity testing.
AB - Purpose To determine if Hardy-Rand-Rittler (H-R-R) and Ishihara testing are accurate estimates of color vision in subjects with acquired visual dysfunction. Design Assessment of diagnostic tools. Methods Twenty-two subjects with optic neuropathy (aged 18-65) and 18 control subjects were recruited prospectively from an outpatient clinic. Individuals with visual acuity (VA) <20/200 or with congenital color blindness were excluded. All subjects underwent a comprehensive eye examination including VA, color vision, and contrast sensitivity testing. Color vision was assessed using H-R-R and Ishihara plates and Farnsworth D-15 (D-15) discs. D-15 is the accepted standard for detecting and classifying color vision deficits. Contrast sensitivity was measured using Pelli-Robson contrast sensitivity charts. Results No relationship was found between H-R-R and D-15 scores (P =.477). H-R-R score and contrast sensitivity were positively correlated (P =.003). On multivariate analysis, contrast sensitivity (β = 8.61, P <.001) and VA (β = 2.01, P =.022) both showed association with H-R-R scores. Similar to H-R-R, Ishihara score did not correlate with D-15 score (P =.973), but on multivariate analysis was related to contrast sensitivity (β = 8.69, P <.001). H-R-R and Ishihara scores had an equivalent relationship with contrast sensitivity (P =.069). Conclusion Neither H-R-R nor Ishihara testing appears to assess color identification in patients with optic neuropathy. Both H-R-R and Ishihara testing are correlated with contrast sensitivity, and these tests may be useful clinical surrogates for contrast sensitivity testing.
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U2 - 10.1016/j.ajo.2015.06.015
DO - 10.1016/j.ajo.2015.06.015
M3 - Article
C2 - 26116263
AN - SCOPUS:84939258681
SN - 0002-9394
VL - 160
SP - 547-552.e1
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 3
ER -