Clinical Cancer Genetics Disparities among Latinos

Marcia Cruz-Correa, Julyann Pérez-Mayoral, Julie Dutil, Miguel Echenique, Rafael Mosquera, Keila Rivera-Román, Sharee Umpierre, Segundo Rodriguez-Quilichini, Maria Gonzalez-Pons, Myrta I. Olivera, Sherly Pardo, Behalf Of The Puerto Rico Clinical Cancer Genetics Consortia On Behalf Of The Puerto Rico Clinical Cancer Genetics Consortia

Research output: Contribution to journalArticle

Abstract

The three major hereditary cancer syndromes in Latinos (Hereditary Breast and Ovarian Cancer, Familial Adenomatous Polyposis and Lynch Syndrome) have been shown to exhibit geographic disparities by country of origin suggesting admixture-based disparities. A solid infrastructure of clinical genetics geared towards diagnosis and prevention could aid in reducing the mortality of these cancer syndromes in Latinos. Currently, clinical cancer genetic services in Latin America are scarce. Moreover, limited studies have investigated the mutational spectrum of these cancer syndromes in Latinos resulting in gaps in personalized medicine affecting diagnosis, treatment and prevention. The following commentary discusses available genotype and clinical information on hereditary cancer in Latinos and highlights the limited access for cancer genetic services in Latin America including barriers to genetic testing and alternatives for providing better access to genetic services. In this review, we discuss the status of clinical genetic cancer services for both US Latinos and those Latinos living in Latin America.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalJournal of Genetic Counseling
DOIs
StateAccepted/In press - Dec 12 2016
Externally publishedYes

Fingerprint

Hispanic Americans
Genetic Services
Latin America
Neoplasms
Adenomatous Polyposis Coli
Hereditary Neoplastic Syndromes
Hereditary Nonpolyposis Colorectal Neoplasms
Precision Medicine
Genetic Testing
Ovarian Neoplasms
Genotype
Breast Neoplasms
Mortality

Keywords

  • Genetic counseling
  • Genetic testing
  • Health disparities
  • Hereditary cancer
  • Hispanics

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Cruz-Correa, M., Pérez-Mayoral, J., Dutil, J., Echenique, M., Mosquera, R., Rivera-Román, K., ... On Behalf Of The Puerto Rico Clinical Cancer Genetics Consortia, B. O. T. P. R. C. C. G. C. (Accepted/In press). Clinical Cancer Genetics Disparities among Latinos. Journal of Genetic Counseling, 1-8. https://doi.org/10.1007/s10897-016-0051-x

Clinical Cancer Genetics Disparities among Latinos. / Cruz-Correa, Marcia; Pérez-Mayoral, Julyann; Dutil, Julie; Echenique, Miguel; Mosquera, Rafael; Rivera-Román, Keila; Umpierre, Sharee; Rodriguez-Quilichini, Segundo; Gonzalez-Pons, Maria; Olivera, Myrta I.; Pardo, Sherly; On Behalf Of The Puerto Rico Clinical Cancer Genetics Consortia, Behalf Of The Puerto Rico Clinical Cancer Genetics Consortia.

In: Journal of Genetic Counseling, 12.12.2016, p. 1-8.

Research output: Contribution to journalArticle

Cruz-Correa, M, Pérez-Mayoral, J, Dutil, J, Echenique, M, Mosquera, R, Rivera-Román, K, Umpierre, S, Rodriguez-Quilichini, S, Gonzalez-Pons, M, Olivera, MI, Pardo, S & On Behalf Of The Puerto Rico Clinical Cancer Genetics Consortia, BOTPRCCGC 2016, 'Clinical Cancer Genetics Disparities among Latinos', Journal of Genetic Counseling, pp. 1-8. https://doi.org/10.1007/s10897-016-0051-x
Cruz-Correa M, Pérez-Mayoral J, Dutil J, Echenique M, Mosquera R, Rivera-Román K et al. Clinical Cancer Genetics Disparities among Latinos. Journal of Genetic Counseling. 2016 Dec 12;1-8. https://doi.org/10.1007/s10897-016-0051-x
Cruz-Correa, Marcia ; Pérez-Mayoral, Julyann ; Dutil, Julie ; Echenique, Miguel ; Mosquera, Rafael ; Rivera-Román, Keila ; Umpierre, Sharee ; Rodriguez-Quilichini, Segundo ; Gonzalez-Pons, Maria ; Olivera, Myrta I. ; Pardo, Sherly ; On Behalf Of The Puerto Rico Clinical Cancer Genetics Consortia, Behalf Of The Puerto Rico Clinical Cancer Genetics Consortia. / Clinical Cancer Genetics Disparities among Latinos. In: Journal of Genetic Counseling. 2016 ; pp. 1-8.
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