Clinical aspects with regard to the occurrence of an endogenous luteinizing hormone surge in gonadotropin-induced normal menstrual cycles

Jan F.H.M. Van Uem, Jairo E. Garcia, Hung C. Liu, Zev Rosenwaks

Research output: Contribution to journalArticle

Abstract

A decline in serum E2 the day before laparoscopy indicated that ovulation had occurred in 16 cycles stimulated with exogenous gonadotropins for the purpose of in vitro fertilization (IVF). In contrast to 18 control cycles with rising E2 values after human chorionic gonadotropin (hCG) administration and without evidence of ovulation, the onset of the endogenous luteinizing hormone (LH) surge had been initiated. From this study, it is believed that the onset of an endogenous LH surge can be identified by the terminal preovulatory E2 pattern. Further, the incidence of an endogenous LH surge in gonadotropin-induced menstrual cycles and the present clinical approach of the Norfolk IVF program to this phenomenon are discussed.

Original languageEnglish (US)
Pages (from-to)345-349
Number of pages5
JournalJournal of In Vitro Fertilization and Embryo Transfer
Volume3
Issue number6
DOIs
StatePublished - Dec 1 1986
Externally publishedYes

Keywords

  • gonadotropins
  • in vitro fertilization
  • luteinizing hormone (LH) surge
  • terminal E pattern

ASJC Scopus subject areas

  • Reproductive Medicine
  • Embryology
  • Obstetrics and Gynecology
  • Developmental Biology

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