TY - JOUR
T1 - Clinical aspects of the management of elderly women diagnosed with gynecologic malignancies
T2 - Treatment decisions and choices
AU - Díaz-Montes, Teresa P.
AU - Levinson, Kimberly
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2011/4
Y1 - 2011/4
N2 - The number of elderly women diagnosed with gynecologic cancer is increasing. This paper reviews the current trends in the management of elderly gynecologic cancer patients. Our goal is to identify critical issues that must be weighed when selecting treatment for elderly gynecologic oncology patients. As individuals continue to achieve longer lifespans, and the population of elderly women continues to grow, gynecologic oncologists will face new challenges regarding treatment. Due to minimal inclusion in randomized controlled trials and the influence of selection bias in many of the current studies, little evidence-based data is available regarding the most effective treatment options for this population. It is therefore unclear whether treatment should differ from that offered to younger populations, and if so under what circumstances. As of yet, there are no validated measures by which to determine tolerability and success of aggressive therapies for this population. Ultimately, each patient must be evaluated individually with regards to risk factors and prognosis, and therapy should not be withheld from elderly individuals solely on the basis of age alone.
AB - The number of elderly women diagnosed with gynecologic cancer is increasing. This paper reviews the current trends in the management of elderly gynecologic cancer patients. Our goal is to identify critical issues that must be weighed when selecting treatment for elderly gynecologic oncology patients. As individuals continue to achieve longer lifespans, and the population of elderly women continues to grow, gynecologic oncologists will face new challenges regarding treatment. Due to minimal inclusion in randomized controlled trials and the influence of selection bias in many of the current studies, little evidence-based data is available regarding the most effective treatment options for this population. It is therefore unclear whether treatment should differ from that offered to younger populations, and if so under what circumstances. As of yet, there are no validated measures by which to determine tolerability and success of aggressive therapies for this population. Ultimately, each patient must be evaluated individually with regards to risk factors and prognosis, and therapy should not be withheld from elderly individuals solely on the basis of age alone.
KW - Cancer
KW - Elderly women
KW - Gynecologic oncology
KW - Radiation
KW - Surgery
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=79952618139&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79952618139&partnerID=8YFLogxK
U2 - 10.1016/j.jgo.2010.11.001
DO - 10.1016/j.jgo.2010.11.001
M3 - Review article
AN - SCOPUS:79952618139
SN - 1879-4068
VL - 2
SP - 99
EP - 104
JO - Journal of Geriatric Oncology
JF - Journal of Geriatric Oncology
IS - 2
ER -