Clinical application of a modular genomics technique in systemic lupus erythematosus: Progress towards precision medicine

Eric Zollars, Sean M. Courtney, Bethany J. Wolf, Norm Allaire, Ann Ranger, Gary Hardiman, Michelle Petri

Research output: Contribution to journalArticle

Abstract

Monitoring disease activity in a complex, heterogeneous disease such as lupus is difficult. Both over- and undertreatment lead to damage. Current standard of care serologies are unreliable. Better measures of disease activity are necessary as we move into the era of precision medicine. We show here the use of a data-driven, modular approach to genomic biomarker development within lupus - specifically lupus nephritis.

Original languageEnglish (US)
Article number7862962
JournalInternational Journal of Genomics
Volume2016
DOIs
Publication statusPublished - 2016

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Genetics
  • Pharmaceutical Science

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