Clinical and experimental immunobiology of medulloblastomas

M. A. Gerosa, G. Semenzato, G. Amadori, Alessandro Olivi, A. Rotilio, M. Zuccarello

Research output: Contribution to journalArticle

Abstract

A wide pre- and postoperative immunological monitoring of B- and T-cell markers in children with medulloblastomas is presented. Preoperative investigations showed a noticeable failure of T-cell-dependent immunity, currently identified by 'active' E-rosette forming cells (Ea-RFC) and blastogenesis tests, with a significant increase of spontaneous cell-mediated cytotoxicity (SCMC). In postoperative long-term controls, a slight recovery of Ea-RFC and blastogenesis tests was observed. The main findings concerning cytotoxicity kinetics are discussed.

Original languageEnglish (US)
Pages (from-to)193-195
Number of pages3
JournalSurgical Neurology
Volume14
Issue number3
StatePublished - 1980
Externally publishedYes

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Medulloblastoma
Lymphocyte Activation
T-Lymphocytes
Immunologic Monitoring
Immunity

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Gerosa, M. A., Semenzato, G., Amadori, G., Olivi, A., Rotilio, A., & Zuccarello, M. (1980). Clinical and experimental immunobiology of medulloblastomas. Surgical Neurology, 14(3), 193-195.

Clinical and experimental immunobiology of medulloblastomas. / Gerosa, M. A.; Semenzato, G.; Amadori, G.; Olivi, Alessandro; Rotilio, A.; Zuccarello, M.

In: Surgical Neurology, Vol. 14, No. 3, 1980, p. 193-195.

Research output: Contribution to journalArticle

Gerosa, MA, Semenzato, G, Amadori, G, Olivi, A, Rotilio, A & Zuccarello, M 1980, 'Clinical and experimental immunobiology of medulloblastomas', Surgical Neurology, vol. 14, no. 3, pp. 193-195.
Gerosa MA, Semenzato G, Amadori G, Olivi A, Rotilio A, Zuccarello M. Clinical and experimental immunobiology of medulloblastomas. Surgical Neurology. 1980;14(3):193-195.
Gerosa, M. A. ; Semenzato, G. ; Amadori, G. ; Olivi, Alessandro ; Rotilio, A. ; Zuccarello, M. / Clinical and experimental immunobiology of medulloblastomas. In: Surgical Neurology. 1980 ; Vol. 14, No. 3. pp. 193-195.
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