Classical hormones linked to obesity

Hyeong Kyu Park, Rexford S. Ahima

Research output: Chapter in Book/Report/Conference proceedingChapter


Hyperinsulinism, hypercortisolism, hypothyroidism, polycystic ovarian syndrome, and growth hormone deficiency are often associated with obesity. Insulin is a potent anabolic hormone. Treatment with insulin or some antidiabetic drugs results in weight gain through several mechanisms. Insulinoma is a rare cause of hyperinsulinism associated with hypoglycemia, hunger, and rapid weight gain. The etiology of polycystic ovary syndrome (PCOS) is complex and multifactorial. PCOS is often associated with central obesity, insulin resistance, and hyperandrogenemia. Excessive glucocorticoid exposure, such as Cushing's syndrome, results in central obesity, sarcopenia, osteoporosis, hypertension, and hyperlipidemia.

Original languageEnglish (US)
Title of host publicationMetabolic Basis of Obesity
PublisherSpringer New York
Number of pages16
ISBN (Print)9781441916068
StatePublished - Dec 1 2011
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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