Classical hormones linked to obesity

Hyeong Kyu Park, Rexford S. Ahima

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Hyperinsulinism, hypercortisolism, hypothyroidism, polycystic ovarian syndrome, and growth hormone deficiency are often associated with obesity. Insulin is a potent anabolic hormone. Treatment with insulin or some antidiabetic drugs results in weight gain through several mechanisms. Insulinoma is a rare cause of hyperinsulinism associated with hypoglycemia, hunger, and rapid weight gain. The etiology of polycystic ovary syndrome (PCOS) is complex and multifactorial. PCOS is often associated with central obesity, insulin resistance, and hyperandrogenemia. Excessive glucocorticoid exposure, such as Cushing's syndrome, results in central obesity, sarcopenia, osteoporosis, hypertension, and hyperlipidemia.

Original languageEnglish (US)
Title of host publicationMetabolic Basis of Obesity
PublisherSpringer New York
Pages139-154
Number of pages16
ISBN (Print)9781441916068
DOIs
StatePublished - Dec 1 2011

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Park, H. K., & Ahima, R. S. (2011). Classical hormones linked to obesity. In Metabolic Basis of Obesity (pp. 139-154). Springer New York. https://doi.org/10.1007/978-1-4419-1607-5_8