Circulating blood markers and functional impairment in peripheral arterial disease

Mary M. McDermott, Kiang Liu, Luigi Ferrucci, Lu Tian, Jack M. Guralnik, David Green, Jin Tan, Yihua Liao, William H. Pearce, Joseph R. Schneider, Kimberly McCue, Paul Ridker, Nader Rifai, Michael H. Criqui

Research output: Contribution to journalArticle

Abstract

OBJECTIVES: To determine whether higher levels of inflammatory blood markers, D-dimer, and homocysteine were associated with greater impairment in lower extremity functioning in persons with peripheral arterial disease (PAD). DESIGN: Cross-sectional. SETTING: Three Chicago-area medical centers. PARTICIPANTS: Four hundred twenty-three persons with PAD (ankle-brachial index (ABI)

Original languageEnglish (US)
Pages (from-to)1504-1510
Number of pages7
JournalJournal of the American Geriatrics Society
Volume56
Issue number8
DOIs
StatePublished - Aug 2008
Externally publishedYes

Keywords

  • Inflammation
  • Intermittent claudication
  • Peripheral vascular disease
  • Physical functioning

ASJC Scopus subject areas

  • Geriatrics and Gerontology

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  • Cite this

    McDermott, M. M., Liu, K., Ferrucci, L., Tian, L., Guralnik, J. M., Green, D., Tan, J., Liao, Y., Pearce, W. H., Schneider, J. R., McCue, K., Ridker, P., Rifai, N., & Criqui, M. H. (2008). Circulating blood markers and functional impairment in peripheral arterial disease. Journal of the American Geriatrics Society, 56(8), 1504-1510. https://doi.org/10.1111/j.1532-5415.2008.01797.x