Circadian Variations in Mouse Hematopoiesis II. Sex Differences in Mitotic Indices of Femoral Diaphyseal Marrow Cells

Saul J. Sharkis; Joseph Lobue; Peter Alexander; Frederic Rakowitz; Anne Weitz-Hamburger; Albert S. Gordon

doi:10.3181/00379727-138-35926

Circadian Variations in Mouse Hematopoiesis II. Sex Differences in Mitotic Indices of Femoral Diaphyseal Marrow Cells

Saul J. Sharkis, Joseph Lobue, Peter Alexander, Frederic Rakowitz, Anne Weitz-Hamburger, Albert S. Gordon

Research output: Contribution to journal › Article › peer-review

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Abstract

Circadian fluctuations in the mitotic index of 3 specific cell lines of the bone marrow were studied. The males showed bimodal fluctuations for the dividing granulocytes and one peak with two minima for lymphocytes. Erythroid mitotic indices exhibited a clear cut diurnal variation with peak activity in late afternoon and lowest in early morning. No circadian fluctuations could be ascertained for mitotic indices of bone marrow cells from female mice.

Original language	English (US)
Pages (from-to)	494-496
Number of pages	3
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	138
Issue number	2
DOIs	https://doi.org/10.3181/00379727-138-35926
State	Published - Nov 1971
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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title = "Circadian Variations in Mouse Hematopoiesis II. Sex Differences in Mitotic Indices of Femoral Diaphyseal Marrow Cells",

abstract = "Circadian fluctuations in the mitotic index of 3 specific cell lines of the bone marrow were studied. The males showed bimodal fluctuations for the dividing granulocytes and one peak with two minima for lymphocytes. Erythroid mitotic indices exhibited a clear cut diurnal variation with peak activity in late afternoon and lowest in early morning. No circadian fluctuations could be ascertained for mitotic indices of bone marrow cells from female mice.",

author = "Sharkis, {Saul J.} and Joseph Lobue and Peter Alexander and Frederic Rakowitz and Anne Weitz-Hamburger and Gordon, {Albert S.}",

note = "Funding Information: Supported by research Grant 5-R01-HE03357-14 and training Grant 5-T01-HE05645-O6 from the National Heart and Lung Institute of the National Institutes of Health, U.S. Public Health Service and a Bio-Medical Science support grant to New York University. ",

year = "1971",

month = nov,

doi = "10.3181/00379727-138-35926",

language = "English (US)",

volume = "138",

pages = "494--496",

journal = "Proceedings of the Society for Experimental Biology and Medicine",

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T1 - Circadian Variations in Mouse Hematopoiesis II. Sex Differences in Mitotic Indices of Femoral Diaphyseal Marrow Cells

AU - Sharkis, Saul J.

AU - Lobue, Joseph

AU - Alexander, Peter

AU - Rakowitz, Frederic

AU - Weitz-Hamburger, Anne

AU - Gordon, Albert S.

N1 - Funding Information: Supported by research Grant 5-R01-HE03357-14 and training Grant 5-T01-HE05645-O6 from the National Heart and Lung Institute of the National Institutes of Health, U.S. Public Health Service and a Bio-Medical Science support grant to New York University.

PY - 1971/11

Y1 - 1971/11

N2 - Circadian fluctuations in the mitotic index of 3 specific cell lines of the bone marrow were studied. The males showed bimodal fluctuations for the dividing granulocytes and one peak with two minima for lymphocytes. Erythroid mitotic indices exhibited a clear cut diurnal variation with peak activity in late afternoon and lowest in early morning. No circadian fluctuations could be ascertained for mitotic indices of bone marrow cells from female mice.

AB - Circadian fluctuations in the mitotic index of 3 specific cell lines of the bone marrow were studied. The males showed bimodal fluctuations for the dividing granulocytes and one peak with two minima for lymphocytes. Erythroid mitotic indices exhibited a clear cut diurnal variation with peak activity in late afternoon and lowest in early morning. No circadian fluctuations could be ascertained for mitotic indices of bone marrow cells from female mice.

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Circadian Variations in Mouse Hematopoiesis II. Sex Differences in Mitotic Indices of Femoral Diaphyseal Marrow Cells

Abstract

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