Circadian Variations in Mouse Hematopoiesis II. Sex Differences in Mitotic Indices of Femoral Diaphyseal Marrow Cells

Saul J. Sharkis, Joseph Lobue, Peter Alexander, Frederic Rakowitz, Anne Weitz-Hamburger, Albert S. Gordon

Research output: Contribution to journalArticle

Abstract

Circadian fluctuations in the mitotic index of 3 specific cell lines of the bone marrow were studied. The males showed bimodal fluctuations for the dividing granulocytes and one peak with two minima for lymphocytes. Erythroid mitotic indices exhibited a clear cut diurnal variation with peak activity in late afternoon and lowest in early morning. No circadian fluctuations could be ascertained for mitotic indices of bone marrow cells from female mice.

Original languageEnglish (US)
Pages (from-to)494-496
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume138
Issue number2
DOIs
StatePublished - Nov 1971

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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