Ciliary body melanoma with limited nodular extrascleral extension and diffuse iris-angle infiltration treated by whole anterior segment plaque radiotherapy

Michael E. Gray, Zélia M. Corrêa, James J. Augsburger, William Barrett

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Primary uveal malignant melanoma of the ciliary body associated with nodular extrascleral extension, diffuse iris-angle infiltration, and secondary glaucoma is usually treated by prompt enucleation. We report a patient with ciliary body melanoma associated with nodular extrascleral extension and diffuse infiltration of the iris and angle treated conservatively because the fellow eye was blind. Methods: The clinical features and surgical management of a melanoma of the ciliary body with extrascleral extension and diffuse infiltration of the iris and angle are presented. The tumor was treated with focal I-125 plaque radiotherapy followed by supplemental whole anterior segment I-125 plaque radiotherapy. Results: The patient has been followed for over 2.5 years since the initial plaque radiotherapy and over 1.5 years since the supplemental whole anterior segment radiotherapy. His visual acuity is correctable to 20/40 OD and there is no evidence of metastatic disease. His glaucoma is well controlled following trabeculectomy and tube shunt procedure. Conclusion: Whole anterior segment plaque radiotherapy for ciliary body melanoma with diffuse iris-angle infiltration provided palliative local tumor control without significant local complications through available follow-up.

Original languageEnglish (US)
Pages (from-to)273-276
Number of pages4
JournalInternational Ophthalmology
Volume27
Issue number4
DOIs
StatePublished - Aug 2007
Externally publishedYes

Keywords

  • Conservative therapy
  • Eye
  • Ocular melanoma
  • Plaque radiotherapy
  • Secondary glaucoma

ASJC Scopus subject areas

  • Ophthalmology

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