Chronic wound repair and healing in older adults: Current status and future research

Lisa Gould, Peter Abadir, Harold Brem, Marissa Carter, Teresa Conner-Kerr, Jeff Davidson, Luisa Dipietro, Vincent Falanga, Caroline Fife, Sue Gardner, Elizabeth Grice, John Harmon, William R. Hazzard, Kevin P. High, Pamela Houghton, Nasreen Jacobson, Robert S. Kirsner, Elizabeth J. Kovacs, David Margolis, Frances McFarland Horne & 9 others May J. Reed, Dennis H. Sullivan, Stephen Thom, Marjana Tomic-Canic, Jeremy Walston, Joanne Whitney, John Williams, Susan Zieman, Kenneth Schmader

Research output: Contribution to journalArticle

Abstract

The incidence of chronic wounds is increased among older adults, and the impact of chronic wounds on quality of life is particularly profound in this population. It is well established that wound healing slows with age. However, the basic biology underlying chronic wounds and the influence of age-associated changes on wound healing are poorly understood. Most studies have used in vitro approaches and various animal models, but observed changes translate poorly to human healing conditions. The impact of age and accompanying multi-morbidity on the effectiveness of existing and emerging treatment approaches for chronic wounds is also unknown, and older adults tend to be excluded from randomized clinical trials. Poorly defined outcomes and variables, lack of standardization in data collection, and variations in the definition, measurement, and treatment of wounds also hamper clinical studies. The Association of Specialty Professors, in conjunction with the National Institute on Aging and the Wound Healing Society, held a workshop, summarized in this paper, to explore the current state of knowledge and research challenges, engage investigators across disciplines, and identify key research questions to guide future study of age-associated changes in chronic wound healing.

LanguageEnglish (US)
Pages1-13
Number of pages13
JournalWound Repair and Regeneration
Volume23
Issue number1
DOIs
StatePublished - Jan 1 2015

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Wound Healing
Wounds and Injuries
National Institute on Aging (U.S.)
Research
Randomized Controlled Trials
Animal Models
Quality of Life
Research Personnel
Morbidity
Education
Incidence
Population

ASJC Scopus subject areas

  • Dermatology
  • Surgery

Cite this

Gould, L., Abadir, P., Brem, H., Carter, M., Conner-Kerr, T., Davidson, J., ... Schmader, K. (2015). Chronic wound repair and healing in older adults: Current status and future research. Wound Repair and Regeneration, 23(1), 1-13. DOI: 10.1111/wrr.12245

Chronic wound repair and healing in older adults : Current status and future research. / Gould, Lisa; Abadir, Peter; Brem, Harold; Carter, Marissa; Conner-Kerr, Teresa; Davidson, Jeff; Dipietro, Luisa; Falanga, Vincent; Fife, Caroline; Gardner, Sue; Grice, Elizabeth; Harmon, John; Hazzard, William R.; High, Kevin P.; Houghton, Pamela; Jacobson, Nasreen; Kirsner, Robert S.; Kovacs, Elizabeth J.; Margolis, David; McFarland Horne, Frances; Reed, May J.; Sullivan, Dennis H.; Thom, Stephen; Tomic-Canic, Marjana; Walston, Jeremy; Whitney, Joanne; Williams, John; Zieman, Susan; Schmader, Kenneth.

In: Wound Repair and Regeneration, Vol. 23, No. 1, 01.01.2015, p. 1-13.

Research output: Contribution to journalArticle

Gould, L, Abadir, P, Brem, H, Carter, M, Conner-Kerr, T, Davidson, J, Dipietro, L, Falanga, V, Fife, C, Gardner, S, Grice, E, Harmon, J, Hazzard, WR, High, KP, Houghton, P, Jacobson, N, Kirsner, RS, Kovacs, EJ, Margolis, D, McFarland Horne, F, Reed, MJ, Sullivan, DH, Thom, S, Tomic-Canic, M, Walston, J, Whitney, J, Williams, J, Zieman, S & Schmader, K 2015, 'Chronic wound repair and healing in older adults: Current status and future research' Wound Repair and Regeneration, vol. 23, no. 1, pp. 1-13. DOI: 10.1111/wrr.12245
Gould L, Abadir P, Brem H, Carter M, Conner-Kerr T, Davidson J et al. Chronic wound repair and healing in older adults: Current status and future research. Wound Repair and Regeneration. 2015 Jan 1;23(1):1-13. Available from, DOI: 10.1111/wrr.12245
Gould, Lisa ; Abadir, Peter ; Brem, Harold ; Carter, Marissa ; Conner-Kerr, Teresa ; Davidson, Jeff ; Dipietro, Luisa ; Falanga, Vincent ; Fife, Caroline ; Gardner, Sue ; Grice, Elizabeth ; Harmon, John ; Hazzard, William R. ; High, Kevin P. ; Houghton, Pamela ; Jacobson, Nasreen ; Kirsner, Robert S. ; Kovacs, Elizabeth J. ; Margolis, David ; McFarland Horne, Frances ; Reed, May J. ; Sullivan, Dennis H. ; Thom, Stephen ; Tomic-Canic, Marjana ; Walston, Jeremy ; Whitney, Joanne ; Williams, John ; Zieman, Susan ; Schmader, Kenneth. / Chronic wound repair and healing in older adults : Current status and future research. In: Wound Repair and Regeneration. 2015 ; Vol. 23, No. 1. pp. 1-13
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