Chronic Spontaneous Urticaria. Etiology and Pathogenesis

Research output: Contribution to journalReview articlepeer-review

Abstract

Urticaria affects individuals of all ages and is commonplace. Nearly 1 in 5 individuals will experience an episode of urticaria in their lifetime, while the chronic form of disease has an estimated annual prevalence of approximately 1% of the population. Given the similarity of chronic urticaria symptoms to those seen in patients suffering an allergic reaction, the condition often leads to a search for an external cause. In most cases, no external trigger factor is identified. At present several theories of pathogenesis exist, none of which is firmly established.

Original languageEnglish (US)
Pages (from-to)33-52
Number of pages20
JournalImmunology and Allergy Clinics of North America
Volume34
Issue number1
DOIs
StatePublished - Feb 1 2014

Keywords

  • Basophils
  • Chronic urticaria
  • Mast cells

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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