Chronic pulmonary histoplasmosis: improved lymphocyte response with transfer factor

C. R. Smith, D. E. Griffin, J. R. Graybill

Research output: Contribution to journalArticlepeer-review

Abstract

Infection with Histoplasma capsulatum may cause chronic cavitary pulmonary disease in humans. Approximately 12% to 17% of patients with chronic pulmonary histoplasmosis have an impaired cell mediated immune response to histoplasmin. It has been suggested that this impairment may be reversed by transfer factor. The authors gave 3 U of transfer factor to a patient with anergic chronic pulmonary histoplasmosis and observed transient conversion of his skin test and lymphocyte transformation index (LTI).

Original languageEnglish (US)
Pages (from-to)708-709
Number of pages2
JournalAnnals of internal medicine
Volume84
Issue number6
DOIs
StatePublished - 1976

ASJC Scopus subject areas

  • Internal Medicine

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