TY - JOUR
T1 - Chronic obstructive pulmonary disease and association with mild cognitive impairment
T2 - The Mayo Clinic Study of Aging
AU - Singh, Balwinder
AU - Parsaik, Ajay K.
AU - Mielke, Michelle M.
AU - Roberts, Rosebud O.
AU - Scanlon, Paul D.
AU - Geda, Yonas E.
AU - Pankratz, V. Shane
AU - Christianson, Teresa
AU - Yawn, Barbara P.
AU - Petersen, Ronald C.
PY - 2013
Y1 - 2013
N2 - Objective: To investigate the association of chronic obstructive pulmonary disease (COPD) with mild cognitive impairment (MCI) and MCI subtype: amnestic MCI and nonamnestic MCI, in a populationbased study of elderly patients. Patients and Methods: Participants included 1927 individuals aged 70 to 89 years enrolled in the population-based Mayo Clinic Study of Aging. Participants were evaluated by using a nurse assessment, neurological evaluation, and neuropsychological testing, and the diagnosis of MCI was made by a consensus panel according to the standardized criteria. Chronic obstructive pulmonary disease was identified by the review of medical records. The study was conducted from October 1, 2004, through July 31, 2007. The associations of COPD and disease duration with MCI and its subtypes were evaluated by using logistic regression models adjusted for potential covariates. Results: Of 1927 participants, 288 had COPD (men vs women: 18% vs 12%; P
AB - Objective: To investigate the association of chronic obstructive pulmonary disease (COPD) with mild cognitive impairment (MCI) and MCI subtype: amnestic MCI and nonamnestic MCI, in a populationbased study of elderly patients. Patients and Methods: Participants included 1927 individuals aged 70 to 89 years enrolled in the population-based Mayo Clinic Study of Aging. Participants were evaluated by using a nurse assessment, neurological evaluation, and neuropsychological testing, and the diagnosis of MCI was made by a consensus panel according to the standardized criteria. Chronic obstructive pulmonary disease was identified by the review of medical records. The study was conducted from October 1, 2004, through July 31, 2007. The associations of COPD and disease duration with MCI and its subtypes were evaluated by using logistic regression models adjusted for potential covariates. Results: Of 1927 participants, 288 had COPD (men vs women: 18% vs 12%; P
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U2 - 10.1016/j.mayocp.2013.08.012
DO - 10.1016/j.mayocp.2013.08.012
M3 - Article
C2 - 24182702
AN - SCOPUS:84888868685
SN - 0025-6196
VL - 88
SP - 1222
EP - 1230
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
IS - 11
ER -