TY - JOUR
T1 - Chronic multi-electrode neural recording in free-roaming monkeys
AU - Eliades, Steven J.
AU - Wang, Xiaoqin
N1 - Funding Information:
The authors would like to offer our most sincere thanks to Dr. Bruce McNaughton for kindly demonstrating his multi-electrode techniques to us. We thank the entire team at Neuralynx, which designed and built the Warp16 arrays to our specifications and continue to adapt the design to our ever-changing needs. We would also like to thank Ashley Pistorio for assistance in animal care and training. This work was supported by NIH grant DC005808 (X.W.).
PY - 2008/7/30
Y1 - 2008/7/30
N2 - Many behaviors of interest to neurophysiologists are difficult to study under laboratory conditions because such behaviors are often inhibited when an animal is restrained and socially isolated. Even under the best conditions, such behaviors may be sparse enough as to require long duration neural recordings or simultaneous recording of multiple neurons to gather a sufficient amount of data for analysis. We have developed a preparation for chronic, multi-electrode recordings in the auditory cortex of marmoset monkeys, small primates, as well as techniques for neurophysiological recordings when the animals are free-roaming while singly caged in the environment of the monkey colony. In this report, we describe our solutions to overcome the problems associated with chronic recordings in free-roaming animals, where three-dimensional movements present particular challenges.
AB - Many behaviors of interest to neurophysiologists are difficult to study under laboratory conditions because such behaviors are often inhibited when an animal is restrained and socially isolated. Even under the best conditions, such behaviors may be sparse enough as to require long duration neural recordings or simultaneous recording of multiple neurons to gather a sufficient amount of data for analysis. We have developed a preparation for chronic, multi-electrode recordings in the auditory cortex of marmoset monkeys, small primates, as well as techniques for neurophysiological recordings when the animals are free-roaming while singly caged in the environment of the monkey colony. In this report, we describe our solutions to overcome the problems associated with chronic recordings in free-roaming animals, where three-dimensional movements present particular challenges.
KW - Auditory cortex
KW - Chronic recording
KW - Free-roaming
KW - Implanted electrodes
KW - Marmoset
KW - Multi-electrode arrays
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U2 - 10.1016/j.jneumeth.2008.04.029
DO - 10.1016/j.jneumeth.2008.04.029
M3 - Article
C2 - 18572250
AN - SCOPUS:46249102107
SN - 0165-0270
VL - 172
SP - 201
EP - 214
JO - Journal of Neuroscience Methods
JF - Journal of Neuroscience Methods
IS - 2
ER -