Chronic lung disease of childhood: Control of breathing during wake and sleep

Brian M. McGinley, John L. Carroll

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Control of breathing in infants during wake and sleep is immature at birth and undergoes rapid maturation over the first year of life. Infants with chronic lung disease (CLD) have multiple control of breathing impairments leaving them particularly vulnerable to hypoxic and asphyxic events. These impairments in the control of breathing are thought to contribute significantly to increased morbidity and the increased incidence of sudden infant death in infants with CLD. This review provides an overview of factors integral to the control of breathing during wake and sleep and factors that influence the development of control of breathing with a focus on the impact of CLD.

Original languageEnglish (US)
Pages (from-to)39-43
Number of pages5
JournalPediatric, Allergy, Immunology, and Pulmonology
Issue number1
StatePublished - Mar 1 2011

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine


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