Chronic inflammation role in the obesity-diabetes association: A case-cohort study

Vivian C. Luft, Maria I. Schmidt, James S. Pankow, David Couper, Christie M. Ballantyne, J Hunter Young, Bruce B. Duncan

Research output: Contribution to journalArticle

Abstract

Background: Chronic inflammation is related to both obesity and diabetes. Our aim was to investigate to what extent this inflammation contributes to the association between obesity and diabetes. Methods. Using a case-cohort design, we followed 567 middle-aged individuals who developed diabetes and 554 who did not over 9 years within the ARIC Study. Weighted Cox proportional hazards analyses permitted statistical inference to the entire cohort. Results: Obese individuals (BMI≥30 kg/m§ssup§2§esup§), compared to those with BMI

Original languageEnglish (US)
Article number31
JournalDiabetology and Metabolic Syndrome
Volume5
Issue number1
DOIs
StatePublished - 2013

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Cohort Studies
Obesity
Inflammation

Keywords

  • Adipokines
  • Diabetes
  • Epidemiologic studies
  • Humans
  • Inflammation
  • Obesity

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Luft, V. C., Schmidt, M. I., Pankow, J. S., Couper, D., Ballantyne, C. M., Young, J. H., & Duncan, B. B. (2013). Chronic inflammation role in the obesity-diabetes association: A case-cohort study. Diabetology and Metabolic Syndrome, 5(1), [31]. https://doi.org/10.1186/1758-5996-5-31

Chronic inflammation role in the obesity-diabetes association : A case-cohort study. / Luft, Vivian C.; Schmidt, Maria I.; Pankow, James S.; Couper, David; Ballantyne, Christie M.; Young, J Hunter; Duncan, Bruce B.

In: Diabetology and Metabolic Syndrome, Vol. 5, No. 1, 31, 2013.

Research output: Contribution to journalArticle

Luft, Vivian C. ; Schmidt, Maria I. ; Pankow, James S. ; Couper, David ; Ballantyne, Christie M. ; Young, J Hunter ; Duncan, Bruce B. / Chronic inflammation role in the obesity-diabetes association : A case-cohort study. In: Diabetology and Metabolic Syndrome. 2013 ; Vol. 5, No. 1.
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