Chronic depressive symptoms and Framingham coronary risk in HIV-infected and HIV-uninfected women.

Rebecca M. Schwartz, Ather Mansoor, Tracey E. Wilson, Kathryn Anastos, Susan A. Everson-Rose, Elizabeth Golub, Lakshmi Goparaju, Nancy A. Hessol, Wendy J. Mack, Jason Lazar

Research output: Contribution to journalArticle

Abstract

Depression is common in people with cardiovascular diseases (CVD) and those with HIV, and is a risk factor for CVD-related mortality. However, little is known about whether HIV influences the relationship between depression and cardiovascular risk. A total of 526 HIV-infected and 132 uninfected women from the Women's Interagency HIV Study were included in an analysis of women who completed twice-yearly study visits over 9.5 years. CVD risk was calculated at baseline and approximately 9.5 years later using the Framingham Risk Score (FRS). Chronic depressive symptoms were defined as Center for Epidemiologic Studies Depression Scale scores of 16 or greater at ≥75% of study visits. Over the follow-up period, 22.8% of HIV-infected women and 15.9% of HIV-uninfected women had chronic depressive symptoms (p=0.08). Baseline FRS was similar between HIV-infected and uninfected women (M=-5.70 ± SE=0.30 vs. M=-6.90 ± SE=0.60, p=0.07) as was follow-up FRS (M=0.82 ± SE=0.30 vs. M=-0.44 ± SE=0.73, p=0.11). Among HIV-infected and HIV-uninfected women, together, follow-up FRS was higher among women with chronic depressive symptoms as compared to those without (M=1.3 ± SE=0.6 vs. M=-0.3 ± SE=0.40, p

Original languageEnglish (US)
Pages (from-to)394-403
Number of pages10
JournalAIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
Volume24
Issue number3
DOIs
StatePublished - 2012
Externally publishedYes

Fingerprint

HIV
Depression
Cardiovascular Diseases
Disease
mortality
Epidemiologic Studies
Mortality

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chronic depressive symptoms and Framingham coronary risk in HIV-infected and HIV-uninfected women. / Schwartz, Rebecca M.; Mansoor, Ather; Wilson, Tracey E.; Anastos, Kathryn; Everson-Rose, Susan A.; Golub, Elizabeth; Goparaju, Lakshmi; Hessol, Nancy A.; Mack, Wendy J.; Lazar, Jason.

In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, Vol. 24, No. 3, 2012, p. 394-403.

Research output: Contribution to journalArticle

Schwartz, RM, Mansoor, A, Wilson, TE, Anastos, K, Everson-Rose, SA, Golub, E, Goparaju, L, Hessol, NA, Mack, WJ & Lazar, J 2012, 'Chronic depressive symptoms and Framingham coronary risk in HIV-infected and HIV-uninfected women.', AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, vol. 24, no. 3, pp. 394-403. https://doi.org/10.1080/09540121.2011.608791
Schwartz, Rebecca M. ; Mansoor, Ather ; Wilson, Tracey E. ; Anastos, Kathryn ; Everson-Rose, Susan A. ; Golub, Elizabeth ; Goparaju, Lakshmi ; Hessol, Nancy A. ; Mack, Wendy J. ; Lazar, Jason. / Chronic depressive symptoms and Framingham coronary risk in HIV-infected and HIV-uninfected women. In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. 2012 ; Vol. 24, No. 3. pp. 394-403.
@article{af8e7097bc914ba3885a4fd16e72eb5f,
title = "Chronic depressive symptoms and Framingham coronary risk in HIV-infected and HIV-uninfected women.",
abstract = "Depression is common in people with cardiovascular diseases (CVD) and those with HIV, and is a risk factor for CVD-related mortality. However, little is known about whether HIV influences the relationship between depression and cardiovascular risk. A total of 526 HIV-infected and 132 uninfected women from the Women's Interagency HIV Study were included in an analysis of women who completed twice-yearly study visits over 9.5 years. CVD risk was calculated at baseline and approximately 9.5 years later using the Framingham Risk Score (FRS). Chronic depressive symptoms were defined as Center for Epidemiologic Studies Depression Scale scores of 16 or greater at ≥75{\%} of study visits. Over the follow-up period, 22.8{\%} of HIV-infected women and 15.9{\%} of HIV-uninfected women had chronic depressive symptoms (p=0.08). Baseline FRS was similar between HIV-infected and uninfected women (M=-5.70 ± SE=0.30 vs. M=-6.90 ± SE=0.60, p=0.07) as was follow-up FRS (M=0.82 ± SE=0.30 vs. M=-0.44 ± SE=0.73, p=0.11). Among HIV-infected and HIV-uninfected women, together, follow-up FRS was higher among women with chronic depressive symptoms as compared to those without (M=1.3 ± SE=0.6 vs. M=-0.3 ± SE=0.40, p",
author = "Schwartz, {Rebecca M.} and Ather Mansoor and Wilson, {Tracey E.} and Kathryn Anastos and Everson-Rose, {Susan A.} and Elizabeth Golub and Lakshmi Goparaju and Hessol, {Nancy A.} and Mack, {Wendy J.} and Jason Lazar",
year = "2012",
doi = "10.1080/09540121.2011.608791",
language = "English (US)",
volume = "24",
pages = "394--403",
journal = "AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV",
issn = "0954-0121",
publisher = "Routledge",
number = "3",

}

TY - JOUR

T1 - Chronic depressive symptoms and Framingham coronary risk in HIV-infected and HIV-uninfected women.

AU - Schwartz, Rebecca M.

AU - Mansoor, Ather

AU - Wilson, Tracey E.

AU - Anastos, Kathryn

AU - Everson-Rose, Susan A.

AU - Golub, Elizabeth

AU - Goparaju, Lakshmi

AU - Hessol, Nancy A.

AU - Mack, Wendy J.

AU - Lazar, Jason

PY - 2012

Y1 - 2012

N2 - Depression is common in people with cardiovascular diseases (CVD) and those with HIV, and is a risk factor for CVD-related mortality. However, little is known about whether HIV influences the relationship between depression and cardiovascular risk. A total of 526 HIV-infected and 132 uninfected women from the Women's Interagency HIV Study were included in an analysis of women who completed twice-yearly study visits over 9.5 years. CVD risk was calculated at baseline and approximately 9.5 years later using the Framingham Risk Score (FRS). Chronic depressive symptoms were defined as Center for Epidemiologic Studies Depression Scale scores of 16 or greater at ≥75% of study visits. Over the follow-up period, 22.8% of HIV-infected women and 15.9% of HIV-uninfected women had chronic depressive symptoms (p=0.08). Baseline FRS was similar between HIV-infected and uninfected women (M=-5.70 ± SE=0.30 vs. M=-6.90 ± SE=0.60, p=0.07) as was follow-up FRS (M=0.82 ± SE=0.30 vs. M=-0.44 ± SE=0.73, p=0.11). Among HIV-infected and HIV-uninfected women, together, follow-up FRS was higher among women with chronic depressive symptoms as compared to those without (M=1.3 ± SE=0.6 vs. M=-0.3 ± SE=0.40, p

AB - Depression is common in people with cardiovascular diseases (CVD) and those with HIV, and is a risk factor for CVD-related mortality. However, little is known about whether HIV influences the relationship between depression and cardiovascular risk. A total of 526 HIV-infected and 132 uninfected women from the Women's Interagency HIV Study were included in an analysis of women who completed twice-yearly study visits over 9.5 years. CVD risk was calculated at baseline and approximately 9.5 years later using the Framingham Risk Score (FRS). Chronic depressive symptoms were defined as Center for Epidemiologic Studies Depression Scale scores of 16 or greater at ≥75% of study visits. Over the follow-up period, 22.8% of HIV-infected women and 15.9% of HIV-uninfected women had chronic depressive symptoms (p=0.08). Baseline FRS was similar between HIV-infected and uninfected women (M=-5.70 ± SE=0.30 vs. M=-6.90 ± SE=0.60, p=0.07) as was follow-up FRS (M=0.82 ± SE=0.30 vs. M=-0.44 ± SE=0.73, p=0.11). Among HIV-infected and HIV-uninfected women, together, follow-up FRS was higher among women with chronic depressive symptoms as compared to those without (M=1.3 ± SE=0.6 vs. M=-0.3 ± SE=0.40, p

UR - http://www.scopus.com/inward/record.url?scp=84861163999&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861163999&partnerID=8YFLogxK

U2 - 10.1080/09540121.2011.608791

DO - 10.1080/09540121.2011.608791

M3 - Article

C2 - 21902560

AN - SCOPUS:84861163999

VL - 24

SP - 394

EP - 403

JO - AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV

JF - AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV

SN - 0954-0121

IS - 3

ER -