Chromosomal Localization of Four Human VH1-like Protein-Tyrosine Phosphatases

Karen J. Martell, Seung Kwak, David J. Hakes, Jack E. Dixon, Jeffrey M. Trent

Research output: Contribution to journalArticlepeer-review

Abstract

Four human protein-tyrosine phosphatase (PTPase) genes of the VH1-like subclass were cloned by low-stringency screening of a genomic library. These genes were localized to their respective chromosomes by G-banding and fluorescence in situ hybridization. The genes were localized to unique regions of different chromosomes: CL100, a stress-induced PTPase, to 5q35; PAC-1, a mitogen-induced nuclear PTPase, to 2q11; hVH-3 to 10q25; and hVH-4 to 10q11.

Original languageEnglish (US)
Pages (from-to)462-464
Number of pages3
JournalGenomics
Volume22
Issue number2
DOIs
StatePublished - Jul 15 1994

ASJC Scopus subject areas

  • Genetics

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