Choroidal thickness and en face optical coherence tomography imaging in autoimmune retinopathy

Breanna A. Polascik, Dilraj S. Grewal, Kim Jiramongkolchai, Sharon Fekrat

Research output: Contribution to journalArticle

Abstract

A 57-year-old white woman developed autoimmune retinopathy (AIR) in both eyes associated with bilateral autoimmune sensorineural hearing loss. Laboratory testing was positive for 68kDa (heat-shock protein) and 136kDa (human interstitial retinoid-binding protein). Extensive cancer screening was negative. Spectral-domain optical coherence tomography enhanced depth imaging demonstrated a markedly thickened choroid in both eyes. En face imaging showed a distinctive pattern of granular hyperreflective foveal dots. The concurrent sensorineural hearing loss was thought to be of autoimmune origin and also responded to immunosuppressive treatment. Eyes with nonparaneoplastic, seropositive AIR may have associated increased choroidal thickness. Audiology testing should be considered.

Original languageEnglish (US)
Pages (from-to)362-365
Number of pages4
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume47
Issue number4
DOIs
StatePublished - Apr 1 2016
Externally publishedYes

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Optical Coherence Tomography
Sensorineural Hearing Loss
Audiology
Retinol-Binding Proteins
Choroid
Immunosuppressive Agents
Heat-Shock Proteins
Early Detection of Cancer
Therapeutics

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

Cite this

Choroidal thickness and en face optical coherence tomography imaging in autoimmune retinopathy. / Polascik, Breanna A.; Grewal, Dilraj S.; Jiramongkolchai, Kim; Fekrat, Sharon.

In: Ophthalmic Surgery Lasers and Imaging Retina, Vol. 47, No. 4, 01.04.2016, p. 362-365.

Research output: Contribution to journalArticle

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