Despite substantial recent progress in treatment development, choroidal neovascularization (CNV) remains one of the most challenging problems faced by retina specialists. It is a common cause of severe visual loss in patients with age-related macular degeneration (AMD) and younger patients with one of many diseases that affect the choroid-Bruch’s membrane-retinal pigment epithelium (RPE) complex, including but not limited to ocular histoplasmosis, myopic degeneration, angioid streaks, and multifocal choroiditis. As our understanding of the molecular pathogenesis of CNV is increasing, new treatments are being developed which specifically target molecules that are involved. Therefore, it is critical to continue to elucidate the molecular mechanisms involved in CNV.
|Original language||English (US)|
|Title of host publication||Age-Related Macular Degeneration, Second Edition|
|Number of pages||10|
|State||Published - Jan 1 2007|
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