Chondrocyte-cartilage substitute test material

C. G. Frondoza, A. Sohrabi, M. G. Overstreet, P. V. Phan, A. Polotsky, A. Shikani, D. Fink, D. S. Hungerford

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A study was conducted to evaluate the use of cartilage analog micro test system to assess the effect of a fibroblast growth factor-9 (FGF-9), which was mitogenic for chondrocytes. In the process, isolated chondrocytes from nasal cartilage expanded in monolayer were re-seeded onto microcarriers and propagated in spinner culture for 10 days. It was observed that the chondrocytes attached with ease and proliferated on collagen microcarriers. The mitogenic effect of FGF-9 and its ability to enhance certain features on the chondrocyte phenotype were successfully evaluated using the in vitro cartilage analog system.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages595
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

Fingerprint

Cartilage
Fibroblasts
Collagen
Monolayers
Intercellular Signaling Peptides and Proteins

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Frondoza, C. G., Sohrabi, A., Overstreet, M. G., Phan, P. V., Polotsky, A., Shikani, A., ... Hungerford, D. S. (2004). Chondrocyte-cartilage substitute test material. In Transactions - 7th World Biomaterials Congress (pp. 595)

Chondrocyte-cartilage substitute test material. / Frondoza, C. G.; Sohrabi, A.; Overstreet, M. G.; Phan, P. V.; Polotsky, A.; Shikani, A.; Fink, D.; Hungerford, D. S.

Transactions - 7th World Biomaterials Congress. 2004. p. 595.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Frondoza, CG, Sohrabi, A, Overstreet, MG, Phan, PV, Polotsky, A, Shikani, A, Fink, D & Hungerford, DS 2004, Chondrocyte-cartilage substitute test material. in Transactions - 7th World Biomaterials Congress. pp. 595, Transactions - 7th World Biomaterials Congress, Sydney, Australia, 5/17/04.
Frondoza CG, Sohrabi A, Overstreet MG, Phan PV, Polotsky A, Shikani A et al. Chondrocyte-cartilage substitute test material. In Transactions - 7th World Biomaterials Congress. 2004. p. 595
Frondoza, C. G. ; Sohrabi, A. ; Overstreet, M. G. ; Phan, P. V. ; Polotsky, A. ; Shikani, A. ; Fink, D. ; Hungerford, D. S. / Chondrocyte-cartilage substitute test material. Transactions - 7th World Biomaterials Congress. 2004. pp. 595
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