Chondrocyte-cartilage substitute test material

C. G. Frondoza, A. Sohrabi, M. G. Overstreet, P. V. Phan, A. Polotsky, A. Shikani, D. Fink, D. S. Hungerford

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A study was conducted to evaluate the use of cartilage analog micro test system to assess the effect of a fibroblast growth factor-9 (FGF-9), which was mitogenic for chondrocytes. In the process, isolated chondrocytes from nasal cartilage expanded in monolayer were re-seeded onto microcarriers and propagated in spinner culture for 10 days. It was observed that the chondrocytes attached with ease and proliferated on collagen microcarriers. The mitogenic effect of FGF-9 and its ability to enhance certain features on the chondrocyte phenotype were successfully evaluated using the in vitro cartilage analog system.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - Dec 1 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


OtherTransactions - 7th World Biomaterials Congress

ASJC Scopus subject areas

  • Engineering(all)

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