Cholesterol homeostasis: Clipping out a slippery regulator

Research output: Contribution to journalArticle

Abstract

SREBPs are transcriptional activators central to cholesterol homeostasis. Recent work has shown that a two-step cleavage of membrane-bound SREBPs frees them to enter the nucleus. An activator of the first, sterol-regulated proteolysis step has also been identified.

Original languageEnglish (US)
JournalCurrent Biology
Volume7
Issue number3
StatePublished - Jan 1 1997
Externally publishedYes

Fingerprint

Proteolysis
Sterols
proteolysis
sterols
homeostasis
Homeostasis
Cholesterol
cholesterol
Membranes
transactivators

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Cholesterol homeostasis : Clipping out a slippery regulator. / Osborne, Timothy.

In: Current Biology, Vol. 7, No. 3, 01.01.1997.

Research output: Contribution to journalArticle

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