Cholestatic jaundice in the newborn

B. A. Haber, A. M. Lake

Research output: Contribution to journalReview articlepeer-review

Abstract

Neonatal cholestasis or direct hyperbilirubinemia in the first 3 months of life is nearly always more pathologic than physiologic. This article reviews the extensive differential diagnosis of cholestatic jaundice and the approach to diagnosis. A sense of urgency is underscored by the value of early recognition and intervention in metabolic, iatrogenic, and anatomic disorders. The long-term management goals are reviewed, including indications for hepatic transplantation.

Original languageEnglish (US)
Pages (from-to)483-506+ix
JournalClinics in Perinatology
Volume17
Issue number2
DOIs
StatePublished - 1990

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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