Cholera epidemic in Guinea-Bissau (2008)

The importance of "Place"

Francisco J. Luquero, Cunhate Na Banga, Daniel Remartínez, Pedro Pablo Palma, Emanuel Baron, Rebeca F. Grais

Research output: Contribution to journalArticle

Abstract

Background: As resources are limited when responding to cholera outbreaks, knowledge about where to orient interventions is crucial. We describe the cholera epidemic affecting Guinea-Bissau in 2008 focusing on the geographical spread in order to guide prevention and control activities. Methodology/Principal Findings: We conducted two studies: 1) a descriptive analysis of the cholera epidemic in Guinea-Bissau focusing on its geographical spread (country level and within the capital); and 2) a cross-sectional study to measure the prevalence of houses with at least one cholera case in the most affected neighbourhood of the capital (Bairro Bandim) to detect clustering of households with cases (cluster analysis). All cholera cases attending the cholera treatment centres in Guinea-Bissau who fulfilled a modified World Health Organization clinical case definition during the epidemic were included in the descriptive study. For the cluster analysis, a sample of houses was selected from a satellite photo (Google Earth™); 140 houses (and the four closest houses) were assessed from the 2,202 identified structures. We applied K-functions and Kernel smoothing to detect clustering. We confirmed the clustering using Kulldorff's spatial scan statistic. A total of 14,222 cases and 225 deaths were reported in the country (AR = 0.94%, CFR = 1.64%). The more affected regions were Biombo, Bijagos and Bissau (the capital). Bairro Bandim was the most affected neighborhood of the capital (AR = 4.0). We found at least one case in 22.7% of the houses (95%CI: 19.5-26.2) in this neighborhood. The cluster analysis identified two areas within Bairro Bandim at highest risk: a market and an intersection where runoff accumulates waste (p

Original languageEnglish (US)
Article numbere19005
JournalPLoS One
Volume6
Issue number5
DOIs
StatePublished - 2011
Externally publishedYes

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Guinea-Bissau
cholera
Cholera
Cluster Analysis
Cluster analysis
Economics
cluster analysis
descriptive studies
Runoff
World Health Organization
cross-sectional studies
Earth (planet)
Disease Outbreaks
Health
Statistics
Satellites
households
runoff
statistics
Cross-Sectional Studies

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Luquero, F. J., Banga, C. N., Remartínez, D., Palma, P. P., Baron, E., & Grais, R. F. (2011). Cholera epidemic in Guinea-Bissau (2008): The importance of "Place". PLoS One, 6(5), [e19005]. https://doi.org/10.1371/journal.pone.0019005

Cholera epidemic in Guinea-Bissau (2008) : The importance of "Place". / Luquero, Francisco J.; Banga, Cunhate Na; Remartínez, Daniel; Palma, Pedro Pablo; Baron, Emanuel; Grais, Rebeca F.

In: PLoS One, Vol. 6, No. 5, e19005, 2011.

Research output: Contribution to journalArticle

Luquero, FJ, Banga, CN, Remartínez, D, Palma, PP, Baron, E & Grais, RF 2011, 'Cholera epidemic in Guinea-Bissau (2008): The importance of "Place"', PLoS One, vol. 6, no. 5, e19005. https://doi.org/10.1371/journal.pone.0019005
Luquero FJ, Banga CN, Remartínez D, Palma PP, Baron E, Grais RF. Cholera epidemic in Guinea-Bissau (2008): The importance of "Place". PLoS One. 2011;6(5). e19005. https://doi.org/10.1371/journal.pone.0019005
Luquero, Francisco J. ; Banga, Cunhate Na ; Remartínez, Daniel ; Palma, Pedro Pablo ; Baron, Emanuel ; Grais, Rebeca F. / Cholera epidemic in Guinea-Bissau (2008) : The importance of "Place". In: PLoS One. 2011 ; Vol. 6, No. 5.
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