Cholangiocarcinoma treatment

Halim Charbel, Firas Al Kawas

Research output: Contribution to journalArticle

Abstract

Cholangiocarcinoma (CCA) is a tumor of the bile ducts that usually presents with biliary obstruction and has a poor prognosis. The treatment of CCA is challenging as the tumor is usually diagnosed late and the treatments are not very effective except when complete surgical resection is possible. In carefully selected patients, liver transplant can be a curative therapy. In the majority of cases, complete surgical resection is not possible and palliation is the mainstay of treatment. Stenting, using plastic or metallic stents, allows for biliary drainage. Photodynamic therapy plays a role in palliation and might play a role in adjuvant or neoadjuvant therapy. While radiation and chemotherapy can be beneficial, newer ablative techniques and targeted chemotherapies are promising.

Original languageEnglish (US)
Pages (from-to)528-533
Number of pages6
JournalCurrent Gastroenterology Reports
Volume14
Issue number6
DOIs
StatePublished - Dec 2012
Externally publishedYes

Fingerprint

Cholangiocarcinoma
Drug Therapy
Neoadjuvant Therapy
Photochemotherapy
Therapeutics
Bile Ducts
Plastics
Stents
Drainage
Neoplasms
Radiation
Transplants
Liver

Keywords

  • Biliary
  • Cholangiocarcinoma
  • Ercp
  • Klatskin tumor

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Cholangiocarcinoma treatment. / Charbel, Halim; Al Kawas, Firas.

In: Current Gastroenterology Reports, Vol. 14, No. 6, 12.2012, p. 528-533.

Research output: Contribution to journalArticle

Charbel, Halim ; Al Kawas, Firas. / Cholangiocarcinoma treatment. In: Current Gastroenterology Reports. 2012 ; Vol. 14, No. 6. pp. 528-533.
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