Chloride transport in the ferret trachea

G. A. Gerencser; G. M. Loughlin; M. A. Crowder

doi:10.1016/S1095-6433(98)10142-3

Chloride transport in the ferret trachea

G. A. Gerencser, G. M. Loughlin, M. A. Crowder

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4 Scopus citations

Abstract

A net secretion of chloride stimulated by carbamylcholine was observed in whole trachea. Luminal anthracene-9-carboxylic acid inhibited the net secretion of chloride and the transepithelial potential difference across the isolated trachea. Submucosal ouabain inhibited the net secretion of chloride and submucosal ouabain, or submucosal bumetanide inhibited the transepithelial potential difference across the isolated trachea. Short- circuited flat sheets of trachea manifested a net secretion of chloride induced by carbamylcholine. Serosal ouabain inhibited the short-circuit current and net chloride flux across isolated flat sheets of trachea.

Original language	English (US)
Pages (from-to)	93-97
Number of pages	5
Journal	Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology
Volume	122
Issue number	1
DOIs	https://doi.org/10.1016/S1095-6433(98)10142-3
State	Published - Jan 1 1999

Keywords

Chloride secretion
Epithelium
Mustela putorius furo
Trachea
Transport inhibitors

ASJC Scopus subject areas

Biochemistry
Physiology
Molecular Biology

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10.1016/S1095-6433(98)10142-3

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title = "Chloride transport in the ferret trachea",

abstract = "A net secretion of chloride stimulated by carbamylcholine was observed in whole trachea. Luminal anthracene-9-carboxylic acid inhibited the net secretion of chloride and the transepithelial potential difference across the isolated trachea. Submucosal ouabain inhibited the net secretion of chloride and submucosal ouabain, or submucosal bumetanide inhibited the transepithelial potential difference across the isolated trachea. Short- circuited flat sheets of trachea manifested a net secretion of chloride induced by carbamylcholine. Serosal ouabain inhibited the short-circuit current and net chloride flux across isolated flat sheets of trachea.",

keywords = "Chloride secretion, Epithelium, Mustela putorius furo, Trachea, Transport inhibitors",

author = "Gerencser, {G. A.} and Loughlin, {G. M.} and Crowder, {M. A.}",

note = "Funding Information: This study was supported by the Eppley Foundation for Research, and by a Pediatric Pulmonary Center Award (A 2018) from the Division of Maternal and Child Health of the Department of Health and Human Services. Frank Robbins is acknowledged for his excellent technical skills.",

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AU - Loughlin, G. M.

AU - Crowder, M. A.

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KW - Chloride secretion

KW - Epithelium

KW - Mustela putorius furo

KW - Trachea

KW - Transport inhibitors

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Chloride transport in the ferret trachea

Abstract

Keywords

ASJC Scopus subject areas

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