Chlamydia trachomatis infection and the risk of perinatal mortality in Hungary

T. Nyári, M. Woodward, G. Mészáaros, J. Karsai, L. Kovács

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Chlamydial infections of the genital tract are thought to often lead to preterm birth, which is the most important perinatal problem in Hungary. Aim of study: A multicenter study was carried out to determine the prevalence of Chlamydia trachomatis infection, risk factors for the infection and to relate the infection to perinatal mortality, accounting for potential confounding effects. Methods: The nucleic acid hybridization method (PACE2 Gen-Probe) was applied for the examination of Chlamydia trachomatis. Logistic regression analysis was used to assess risk. Results: A total of 6156 pregnant women were examined for the occurrence of Chlamydia trachomatis. The observed overall rate of chlamydial infection was 5.9 %. Young age (less than 24 years old) (OR and 95 % CI: 1.6 (1.3-2.0)), unmarried status (1.5 (1.2-1.9)) and the high unemployment rate (2.1 (1.6-2.7)) were statistically significant predictors of the infection. In logistic regression analysis, chlamydial infection (1.9 (1.1-3.3)), high unemployment rate (1.5 (1.2-2.2)) and low birth weight (1.7 (1.1-2.7) were significant predictors of perinatal mortality. Conclusions: Testing pregnant women for diseases that can be transmitted perinatally is an important part of obstetric care. Screening for C. trachomatis of unmarried women under 24 years of age is suggested and need increased observation during labor.

Original languageEnglish (US)
Pages (from-to)55-59
Number of pages5
JournalJournal of Perinatal Medicine
Volume29
Issue number1
DOIs
StatePublished - 2001

Keywords

  • Chlamydia trachomatis
  • Perinatal mortality
  • Poor perinatal outcome
  • Preterm birth
  • Preventive care

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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